Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8831808 | 0.80 | KCNH2 (0.36) | MEN1KMT2ANPC1RAB9AALOX5 | |
| SCHEMBL9453365 | 0.79 | MEN1 (0.38) | GSK3BL3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL7099330 | 0.75 | RAB9A (0.38) | NPC1RAB9A | |
| SCHEMBL10911511 | 0.73 | HTR1A (0.43) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL7738668 | 0.73 | MEN1 (0.42) | GSK3BMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9645284 | 0.72 | L3MBTL1 (0.51) | GSK3BL3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL10664727 | 0.72 | MAPT (0.38) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL10407212 | 0.72 | ALDH1A1 (0.43) | L3MBTL1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL8592742 | 0.71 | RAB9A (0.41) | GSK3BMEN1KMT2ANPC1RAB9A | |
| SCHEMBL5418407 | 0.71 | MEN1 (0.43) | GSK3BMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34201-E | Analgesics | ANAQUEST, INC. (US) | 1993-03-23 | — | — | US | disclosed |
| US-5053411-A | Analgesics | ANAQUEST, INC. (US) | 1991-10-01 | — | — | US | disclosed |
| EP-0396282-A2 | N-aryl-N-[4-(heterocyclicalkyl) piperidinyl]amides and pharmaceutical compositions and methods employing such compounds | BOC, INC. (US) | 1990-11-07 | — | — | EP | disclosed |