Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.43 |
| ▸ | TUBB | P07437 | 2/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734550 | 0.86 | GRIN1 (0.50) | KDM4EKMT2AMEN1MAPTEPHX2 | |
| SCHEMBL7742336 | 0.85 | LMNA (0.57) | KDM4EKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL14376795 | 0.75 | SMN1; SMN2 (0.58) | KMT2AMEN1MAPTEPHX2PPARG | |
| SCHEMBL8125879 | 0.74 | KMO (0.55) | KDM4EKMT2AMEN1ALDH1A1EPHX2 | |
| SCHEMBL25274814 | 0.74 | CCR2 (0.58) | KMT2AHSD17B10HTTGRIN1GRIN2B | |
| SCHEMBL7739350 | 0.74 | KDM4E (0.43) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL21384939 | 0.73 | GRIN1 (0.61) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL9725445 | 0.73 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL9725523 | 0.72 | KDM4E (0.48) | KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL5243970 | 0.71 | PGR (0.57) | KDM4EKMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420410-B1 | ADMINISTERING N,N'-SUBSTITUTED BENZIMIDAZOL-2-ONES TO INDUCE APOPTOSIS IN NEOPLASTIC CELLS BUT NOT NORMAL CELLS; ANTICANCER, ANTITUMOR AGENT | CELL PATHWAYS, INC. | 2002-07-16 | — | — | US | disclosed |