Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | FOS | P01100 | 1/20 | 0.59 |
| ▸ | TTR | P02766 | 1/20 | 0.59 |
| ▸ | JUN | P05412 | 1/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.59 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.59 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | AR | P10275 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11969383 | 0.87 | TAAR1 (0.62) | TAAR1TSHRMAPK1FOSTTR | |
| SCHEMBL5833247 | 0.87 | TAAR1 (0.62) | TAAR1TSHRMAPK1FOSTTR | |
| SCHEMBL4612057 | 0.85 | TAAR1 (0.61) | TAAR1TSHRMAPK1FOSTTR | |
| SCHEMBL13219152 | 0.84 | PTPN1 (0.60) | TAAR1TSHRMAPK1FOSTTR | |
| SCHEMBL7768865 | 0.84 | FOS (0.62) | TAAR1TSHRMAPK1FOSTTR | |
| SCHEMBL9885364 | 0.84 | FOS (0.62) | TAAR1TSHRMAPK1FOSTTR | |
| SCHEMBL6313682 | 0.84 | TAAR1 (0.64) | TAAR1TSHRMAPK1FOSTTR | |
| SCHEMBL5889475 | 0.84 | TAAR1 (0.59) | TAAR1TSHRMAPK1FOSTTR | |
| SCHEMBL30128916 | 0.82 | ALDH1A1 (0.58) | TSHRLMNAALDH1A1GAATDP1 | |
| SCHEMBL29185788 | 0.82 | ALDH1A1 (0.58) | TSHRLMNAALDH1A1GAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422233-B2 | Vanilloid fatty hydroxamates as therapeutic anti-inflammatory pharmaceuticals | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-08-23 | — | — | US | disclosed |
| US-20120252891-A1 | Vanilloid Fatty Hydroxamates as Therapeutic Anti-inflammatory Pharmaceuticals | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2012-10-04 | — | — | US | disclosed |
| US-6410700-B1 | Glycan derivatives | MACQUARIE RESEARCH LTD. (AU) | 2002-06-25 | — | — | US | disclosed |
| EP-1021455-A1 | GLYCAN DERIVATIVES | Macquarie Research Ltd. (AU) | 2000-07-26 | — | — | EP | disclosed |
| EP-1021455-A4 | GLYCAN DERIVATIVES | MACQUARIE RES LTD (AU) | 2000-07-26 | — | — | EP | disclosed |
| WO-1998015566-A1 | GLYCAN DERIVATIVES | MACQUARIE RESEARCH LTD. (AU) | 1998-04-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252891-A1 | Vanilloid Fatty Hydroxamates as Therapeutic Anti-inflammatory Pharmaceuticals | FAAH, FAAH2, TRPV1 | TAAR1 2882/4885TSHR 4627/4885MAPK1 1799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.