Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | FOS | P01100 | 1/20 | 0.57 |
| ▸ | TTR | P02766 | 1/20 | 0.57 |
| ▸ | JUN | P05412 | 1/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.57 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.57 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5833247 | 0.85 | TAAR1 (0.62) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL11969383 | 0.85 | TAAR1 (0.62) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL7739503 | 0.84 | TAAR1 (0.61) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL4612057 | 0.84 | TAAR1 (0.61) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL6887289 | 0.83 | CA2 (0.61) | LMNAALDH1A1GAATDP1KDM4E | |
| SCHEMBL30454153 | 0.83 | CA2 (0.61) | LMNAALDH1A1GAATDP1KDM4E | |
| SCHEMBL7768865 | 0.82 | FOS (0.62) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL9885364 | 0.82 | FOS (0.62) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL13219152 | 0.82 | PTPN1 (0.60) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL5889475 | 0.82 | TAAR1 (0.59) | TAAR1TSHRMAPK1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11168050-B2 | Efficient synthesis of amines and amides from alcohols and aldehydes by using cascade catalysis | XP CHEMISTRIES AB (SE) | 2021-11-09 | — | — | US | disclosed |
| CN-103751943-B | Fire extinguishing composition containing nitrogen-containing organic compound | 湖北及安盾消防科技有限公司 | 2020-10-13 | — | — | CN | disclosed |
| EP-3122715-B1 | EFFICIENT SYNTHESIS OF AMINES AND AMIDES FROM ALCOHOLS AND ALDEHYDES BY USING CASCADE CATALYSIS | ORGANOFUEL SWEDEN AB (SE) | 2019-05-01 | — | — | EP | disclosed |
| US-20170174618-A1 | EFFICIENT SYNTHESIS OF AMINES AND AMIDES FROM ALCOHOLS AND ALDEHYDES BY USING CASCADE CATALYSIS | XP CHEMISTRIES AB (SE) | 2017-06-22 | — | — | US | disclosed |
| EP-3122715-A1 | EFFICIENT SYNTHESIS OF AMINES AND AMIDES FROM ALCOHOLS AND ALDEHYDES BY USING CASCADE CATALYSIS | Córdova, Armando (SE) | 2017-02-01 | — | — | EP | disclosed |
| WO-2015144902-A1 | EFFICIENT SYNTHESIS OF AMINES AND AMIDES FROM ALCOHOLS AND ALDEHYDES BY USING CASCADE CATALYSIS | CÓRDOVA ARMANDO (SE) | 2015-10-01 | — | — | WO | disclosed |
| US-20050058729-A1 | Treatment for bacterial infections and related disorders | STAGGS JEFF J (US) | 2005-03-17 | — | — | US | disclosed |
| US-6759064-B2 | ADMINISTERING TO A MAMMAL A COMPOSITION COMPRISING TEA CATECHINS AND VANILLOIDS, IN AMOUNTS EFFECTIVE FOR THERAPY AND PROPHYLAXIS OF CANCER | PURDUE RESEARCH FOUNDATION | 2004-07-06 | — | — | US | disclosed |
| US-6593371-B1 | Treatment for wart and related disorders | STAGGS JEFF J (US) | 2003-07-15 | — | — | US | disclosed |
| US-20030072821-A1 | Compositions based on vanilloid-catechin synergies for prevention and treatment of cancer | PURDUE RESEARCH FOUNDATION | 2003-04-17 | — | — | US | disclosed |
| US-6063381-A | THERAPY FOR DEEP TISSUE OR FUNGICIDE | STAGGS JEFF J (US) | 2000-05-16 | — | — | US | disclosed |
| WO-1993023061-A1 | THERAPEUTIC USES OF PUNGENT BOTANICALS AND THEIR RELATED COMPOUNDS | STAGGS JEFF J (US) | 1993-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174618-A1 | EFFICIENT SYNTHESIS OF AMINES AND AMIDES FROM ALCOHOLS AND ALDEHYDES BY USING CASCADE CATALYSIS | ADH5, ADH1A, ADH1C | TAAR1 351/4885TSHR 4756/4885MAPK1 2879/4885 |
| US-11168050-B2 | Efficient synthesis of amines and amides from alcohols and aldehydes by using cascade catalysis | ADH5, ADH1A, ADH1C | TAAR1 351/4885TSHR 4756/4885MAPK1 2879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.