Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 1.00 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | HTR2B | P41595 | 3/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741709 | 0.90 | HTR1A (0.81) | HTR1AHTR2AHTR2CHTR2BMTNR1A | |
| SCHEMBL7741724 | 0.80 | HTR1A (0.67) | HTR1AMTNR1AMTNR1B | |
| SCHEMBL7740272 | 0.80 | HTR1A (0.66) | HTR1AHTR2CMTNR1AMTNR1B | |
| SCHEMBL7741698 | 0.79 | HTR1A (0.65) | HTR1AHTR2AMTNR1AMTNR1B | |
| SCHEMBL7743295 | 0.77 | HTR1A (0.63) | HTR1AMTNR1AMTNR1B | |
| SCHEMBL7740264 | 0.77 | MTNR1B (0.69) | HTR1AMTNR1AMTNR1B | |
| SCHEMBL7740269 | 0.77 | MTNR1B (0.61) | HTR1AMTNR1AMTNR1B | |
| SCHEMBL6634512 | 0.75 | MTNR1A (0.64) | HTR1AHTR2AMTNR1AMTNR1B | |
| SCHEMBL6636372 | 0.75 | MTNR1B (0.66) | HTR1AMTNR1AMTNR1B | |
| SCHEMBL7743321 | 0.74 | HTR1A (0.58) | HTR1AHTR2AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |