Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.65 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.65 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740360 | 0.90 | MTNR1A (0.67) | MTNR1AMTNR1BHTR2AHTR2CHTR2B | |
| SCHEMBL7735737 | 0.81 | MTNR1A (0.72) | MTNR1AMTNR1B | |
| SCHEMBL7735692 | 0.79 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL7741788 | 0.78 | MTNR1B (0.67) | MTNR1AMTNR1B | |
| SCHEMBL6636125 | 0.76 | MTNR1A (0.67) | MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL7743440 | 0.75 | MTNR1A (0.65) | MTNR1AMTNR1B | |
| SCHEMBL7740248 | 0.75 | HTR1A (0.56) | MTNR1AMTNR1B | |
| SCHEMBL7735707 | 0.75 | DRD2 (0.46) | MTNR1AMTNR1BHTR2AHTR2CHTR2B | |
| SCHEMBL6635793 | 0.74 | MTNR1B (0.65) | MTNR1AMTNR1B | |
| SCHEMBL6636448 | 0.69 | MTNR1A (0.64) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |