Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740890 | 0.89 | KDM4A (0.38) | CA1CA2ADRB2HTR1ANAMPT | |
| SCHEMBL7739219 | 0.74 | PPARA (0.40) | MAPT | |
| SCHEMBL7740843 | 0.74 | XDH (0.42) | MAPTTDP1LMNAALDH1A1HPGD | |
| SCHEMBL24162731 | 0.73 | NQO2 (0.45) | NQO2ADRB2HTR1AHTR2CIDO1 | |
| SCHEMBL7737805 | 0.72 | CYP4F2 (0.45) | TDP1ALDH1A1NPSR1 | |
| SCHEMBL7732390 | 0.72 | PPARA (0.40) | MAPTTDP1ALDH1A1HPGDKDM4E | |
| SCHEMBL7740836 | 0.71 | ALDH1A1 (0.39) | MAPTLMNAALDH1A1HPGDHTT | |
| SCHEMBL24199938 | 0.71 | GLS (0.54) | CA1NAMPTIDO1 | |
| SCHEMBL7732384 | 0.71 | XDH (0.44) | MAPTLMNAALDH1A1HPGDHTT | |
| SCHEMBL694269 | 0.70 | CA2 (0.54) | NQO2MAPTTDP1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6416861-B1 | COMBINATORIAL CHEMISTRY | NORTHWESTERN UNIVERSITY | 2002-07-09 | — | — | US | disclosed |
| WO-2000049022-A2 | ORGANOSILICON COMPOUNDS AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2000-08-24 | — | — | WO | disclosed |