Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740857 | 0.89 | NQO2 (0.43) | NAMPTADRB2HTR1AMEN1KMT2A | |
| SCHEMBL24199938 | 0.78 | GLS (0.54) | KDM4AL3MBTL1NAMPTHDAC1GLS | |
| SCHEMBL7739219 | 0.76 | PPARA (0.40) | PPARA | |
| SCHEMBL7732390 | 0.73 | PPARA (0.40) | L3MBTL1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL7732384 | 0.72 | XDH (0.44) | MEN1KMT2APTGS1GAAPPARA | |
| SCHEMBL7738413 | 0.71 | PPARA (0.36) | L3MBTL1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL7732427 | 0.71 | ALDH1A1 (0.40) | L3MBTL1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL28370905 | 0.71 | DYRK1A (0.47) | KDM4AL3MBTL1NAMPTNPC1RAB9A | |
| SCHEMBL30493018 | 0.71 | DYRK1A (0.47) | KDM4AL3MBTL1NAMPTNPC1RAB9A | |
| SCHEMBL3180689 | 0.70 | L3MBTL1 (0.61) | KDM4AL3MBTL1HDAC10HDAC6NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6416861-B1 | COMBINATORIAL CHEMISTRY | NORTHWESTERN UNIVERSITY | 2002-07-09 | — | — | US | disclosed |
| WO-2000049022-A2 | ORGANOSILICON COMPOUNDS AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2000-08-24 | — | — | WO | disclosed |