Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.51 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13885737 | 0.85 | RAB9A (0.58) | HDAC1RAB9ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7748111 | 0.84 | RAB9A (0.83) | HDAC1RAB9ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL28652032 | 0.84 | KCNMA1 (0.60) | HDAC1RAB9ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL3528827 | 0.84 | MAPT (0.62) | HDAC1RAB9ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL29396019 | 0.82 | RAB9A (0.56) | HDAC1RAB9ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6170575 | 0.82 | POLB (0.67) | HDAC1RAB9AHDAC8HDAC6MEN1 | |
| SCHEMBL30008296 | 0.82 | POLB (0.67) | HDAC1RAB9AHDAC8HDAC6MEN1 | |
| SCHEMBL6588596 | 0.81 | HDAC1 (0.77) | HDAC1RAB9ACYP1A2CYP2C19MEN1 | |
| SCHEMBL2755850 | 0.81 | KIF11 (0.51) | HDAC1RAB9ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL30369924 | 0.81 | HDAC1 (0.77) | HDAC1RAB9ACYP1A2CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107734969-A | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 美国陶氏益农公司 | 2018-02-23 | — | — | CN | disclosed |
| EP-1129075-A1 | N-ARYL(THIO)ANTHRANILIC ACID AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS VEGF RECEPTOR TYROSINE KINASE INHIBITORS | Novartis AG (CH) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000027820-A1 | N-ARYL(THIO)ANTHRANILIC ACID AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS VEGF RECEPTOR TYROSINE KINASE INHIBITORS | NOVARTIS AG (CH) | 2000-05-18 | — | — | WO | disclosed |