Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 7/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | CDC42 | P60953 | 1/20 | 0.42 |
| ▸ | RAC1 | P63000 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741232 | 1.00 | MTNR1A (0.57) | MTNR1AMTNR1BAKR1C3AKR1C2PTGS1 | |
| SCHEMBL6633664 | 0.78 | MTNR1A (0.62) | MTNR1AMTNR1BAKR1C3AKR1C2PTGS1 | |
| SCHEMBL7741225 | 0.74 | MTNR1A (0.57) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5227187 | 0.72 | MTNR1A (0.59) | MTNR1AMTNR1BCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7741711 | 0.70 | MTNR1A (0.59) | MTNR1AMTNR1BAKR1C3AKR1C2PTGS1 | |
| SCHEMBL8669796 | 0.68 | MTNR1A (0.63) | MTNR1AMTNR1B | |
| SCHEMBL11718070 | 0.68 | KDM4E (0.53) | MTNR1AMTNR1BHSD17B10 | |
| SCHEMBL7741714 | 0.68 | MTNR1A (0.47) | MTNR1AMTNR1BAKR1C3AKR1C2PTGS1 | |
| SCHEMBL8673938 | 0.67 | MTNR1A (0.52) | MTNR1AMTNR1B | |
| SCHEMBL12804630 | 0.66 | MTNR1A (0.61) | MTNR1AMTNR1BAKR1C3AKR1C2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |