Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.67 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743293 | 0.80 | HTR1A (1.00) | HTR1AMTNR1AMTNR1B | |
| SCHEMBL27521986 | 0.78 | HTR1A (0.44) | HTR1A | |
| SCHEMBL7735711 | 0.76 | MTNR1B (0.43) | HTR1AMTNR1AMTNR1B | |
| SCHEMBL7743442 | 0.76 | HTR1A (0.44) | HTR1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL7741706 | 0.70 | HTR1A (0.53) | HTR1A | |
| SCHEMBL7741709 | 0.70 | HTR1A (0.81) | HTR1AMTNR1AMTNR1B | |
| SCHEMBL7735741 | 0.66 | MTNR1A (0.51) | HTR1AMTNR1AMTNR1B | |
| SCHEMBL7740264 | 0.65 | MTNR1B (0.69) | HTR1AMTNR1AMTNR1B | |
| SCHEMBL7741698 | 0.64 | HTR1A (0.65) | HTR1AMTNR1AMTNR1BADRA2AADRA2B | |
| SCHEMBL7740272 | 0.64 | HTR1A (0.66) | HTR1AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |