Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.53 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.48 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.44 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741751 | 1.00 | TAS1R3 (0.53) | TAS1R3TAS1R1TAS1R2MTNR1AMEN1 | |
| SCHEMBL11602838 | 0.87 | MEN1 (0.57) | TAS1R3TAS1R1TAS1R2MTNR1AMEN1 | |
| SCHEMBL14277944 | 0.87 | TAS1R3 (0.64) | TAS1R3TAS1R1TAS1R2MTNR1AMEN1 | |
| SCHEMBL608095 | 0.87 | TAS1R3 (0.64) | TAS1R3TAS1R1TAS1R2MTNR1AMEN1 | |
| SCHEMBL4710772 | 0.79 | CA12 (0.64) | TAS1R3TAS1R1TAS1R2MTNR1AMEN1 | |
| SCHEMBL8501324 | 0.79 | MTNR1A (0.62) | MTNR1AMTNR1B | |
| SCHEMBL4427914 | 0.79 | MTNR1A (0.62) | MTNR1AMTNR1B | |
| SCHEMBL2466357 | 0.79 | MTNR1A (0.62) | MTNR1AMTNR1B | |
| SCHEMBL7743382 | 0.75 | ACHE (0.46) | — | |
| SCHEMBL7740227 | 0.75 | MTNR1A (0.78) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |
| EP-1047664-A1 | NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ADIR ET COMPAGNIE (FR) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999036392-A1 | NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ADIR ET COMPAGNIE (FR) | 1999-07-22 | — | — | WO | disclosed |