Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5484314 | 0.84 | ACHE (0.60) | ACHEPDPK1KDM1AMAOAMAOB | |
| SCHEMBL29112431 | 0.84 | PDPK1 (0.54) | ACHEPDPK1PDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL9630772 | 0.83 | ACHE (0.63) | ACHEPDPK1KDM1AMAOAMAOB | |
| SCHEMBL16254293 | 0.76 | TAS1R3 (0.54) | KDM1AMAOAMAOB | |
| SCHEMBL7743375 | 0.75 | HTR6 (0.49) | — | |
| SCHEMBL7743313 | 0.75 | TAS1R3 (0.53) | — | |
| SCHEMBL7741751 | 0.75 | TAS1R3 (0.53) | — | |
| SCHEMBL7740227 | 0.71 | MTNR1A (0.78) | — | |
| SCHEMBL19594955 | 0.71 | CA1 (0.51) | ACHEPDPK1MAOAPDE4APDE4B | |
| SCHEMBL7743420 | 0.70 | HTR6 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |