Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740965 | 0.85 | TSHR (0.49) | RAB9ASMN1; SMN2TP53MEN1KMT2A | |
| SCHEMBL6480793 | 0.83 | CES1 (0.45) | PKMMEN1KMT2AALDH1A1ALDH2 | |
| SCHEMBL7741368 | 0.79 | RAB9A (0.43) | RAB9AATMLMNAPKMNPSR1 | |
| SCHEMBL8363985 | 0.79 | CYP3A4 (0.40) | RAB9AATMLMNAPKMNPSR1 | |
| SCHEMBL7745462 | 0.79 | POLB (0.46) | LMNAMAPTALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL7740562 | 0.79 | TSHR (0.57) | LMNANPSR1SMN1; SMN2MAPTTP53 | |
| SCHEMBL7745980 | 0.78 | RAB9A (0.54) | RAB9AATMLMNAPKMNPSR1 | |
| SCHEMBL7746706 | 0.76 | CYP3A4 (0.40) | RAB9AATMLMNAPKMNPSR1 | |
| SCHEMBL7746271 | 0.75 | TSHR (0.45) | RAB9ALMNASMN1; SMN2TP53MEN1 | |
| SCHEMBL7741649 | 0.74 | RAB9A (0.40) | RAB9AATMLMNAPKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |