Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16695989 | 0.85 | ALDH1A1 (0.41) | RAB9AATMSMN1; SMN2LMNAPKM | |
| SCHEMBL7741979 | 0.80 | FAAH (0.56) | SMN1; SMN2LMNATP53MAPTGAA | |
| SCHEMBL20769894 | 0.78 | SMN1; SMN2 (0.52) | RAB9AATMSMN1; SMN2NPSR1TP53 | |
| SCHEMBL7745897 | 0.78 | RAB9A (0.46) | RAB9AATMSMN1; SMN2LMNAPKM | |
| SCHEMBL30184968 | 0.78 | TLR8 (0.65) | SMN1; SMN2LMNATP53MAPTMEN1 | |
| SCHEMBL28036974 | 0.78 | TLR8 (0.65) | SMN1; SMN2LMNATP53MAPTMEN1 | |
| SCHEMBL28036451 | 0.78 | TLR8 (0.65) | SMN1; SMN2LMNATP53MAPTMEN1 | |
| SCHEMBL7741401 | 0.76 | MEN1 (0.59) | RAB9ASMN1; SMN2LMNATP53MAPT | |
| SCHEMBL18148387 | 0.76 | RAB9A (0.64) | RAB9ASMN1; SMN2LMNATP53MAPT | |
| SCHEMBL16696060 | 0.76 | PSEN1 (0.40) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |