Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | GRN | P28799 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8445605 | 0.86 | CASP1 (0.35) | SLC6A4SLC6A3SLC6A2KIF11CASP1 | |
| SCHEMBL16691418 | 0.79 | L3MBTL1 (0.41) | CASP1HSD17B10SSTR4TSHR | |
| SCHEMBL6139367 | 0.77 | TSHR (0.38) | KIF11CASP1HSD17B10SSTR4TSHR | |
| SCHEMBL7749385 | 0.75 | KIF11 (0.38) | KIF11CASP1HSD17B10SSTR4TSHR | |
| SCHEMBL7752071 | 0.74 | CASP1 (0.35) | SLC6A4SLC6A3SLC6A2CASP1HSD17B10 | |
| SCHEMBL7768725 | 0.74 | MIF (0.42) | KIF11KMOTSHRMAOAMAOB | |
| SCHEMBL7750623 | 0.73 | SMN1; SMN2 (0.39) | SLC6A4SLC6A3SLC6A2CASP1HSD17B10 | |
| SCHEMBL7752073 | 0.73 | FFAR1 (0.33) | CASP1HSD17B10 | |
| SCHEMBL3519610 | 0.73 | L3MBTL1 (0.45) | CASP1HSD17B10SSTR4TSHR | |
| SCHEMBL7750624 | 0.72 | SMN1; SMN2 (0.36) | SLC6A4SLC6A3SLC6A2CASP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242607-B1 | SUCH AS 4-CYANO-4-(3,4-DICHLOROPHENYL)HEPTANEDIOIC ACID USED AS ANTAGONISTS OF NEUROKININES | SANOFI-SYNTHELABO (FR) | 2001-06-05 | — | — | US | disclosed |
| US-6008360-A | Substituted 3-aryl-3-carboxyalkyl glutaramides, method for preparing same by 4-arylo-4-cyanoheptane dicarboxylic acid cyclisation, and use thereof for preparing 3-aryl-3-hydroxyalkylpiperidines | SANOFI-SYNTHELABO (FR) | 1999-12-28 | — | — | US | disclosed |