SCHEMBL774971

SCHEMBL774971

CCCCCCCCCCCCCCc1ccco1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.59
HPGD P15428 2/20 0.59
CYP3A4 P08684 2/20 0.59
ALOX15 P16050 1/20 0.59
USP2 O75604 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
MAPT P10636 3/20 0.50
HTT P42858 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
THRA P10827 1/20 0.47
THRB P10828 1/20 0.47
CHRM2 P08172 2/20 0.44
KCNH2 Q12809 2/20 0.44
POLB P06746 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
LIPG Q9Y5X9 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-(Heptadecyl)Furan SCHEMBL8165701 1.00 ALDH1A1 (0.59) ALDH1A1HPGDCYP3A4ALOX15USP2
SCHEMBL1863821 1.00 ALDH1A1 (0.59) ALDH1A1HPGDCYP3A4ALOX15USP2
SCHEMBL4882315 1.00 ALDH1A1 (0.59) ALDH1A1HPGDCYP3A4ALOX15USP2
SCHEMBL775269 1.00 ALDH1A1 (0.59) ALDH1A1HPGDCYP3A4ALOX15USP2
SCHEMBL8760661 1.00 ALDH1A1 (0.59) ALDH1A1HPGDCYP3A4ALOX15USP2
SCHEMBL8760515 1.00 ALDH1A1 (0.59) ALDH1A1HPGDCYP3A4ALOX15USP2
SCHEMBL2706580 1.00 ALDH1A1 (0.59) ALDH1A1HPGDCYP3A4ALOX15USP2
SCHEMBL8760670 1.00 ALDH1A1 (0.59) ALDH1A1HPGDCYP3A4ALOX15USP2
SCHEMBL1514965 1.00 ALDH1A1 (0.59) ALDH1A1HPGDCYP3A4ALOX15USP2
SCHEMBL3384661 1.00 ALDH1A1 (0.59) ALDH1A1HPGDCYP3A4ALOX15USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120071551-A1 ETHANOLIC EXTRACTS OF HASS AVOCADO SEEDS, Persea americana Mill., AND ITS USE AS MITICIDE FOR Panonychus citri, Oligonychus yothersi, AND Tetranychus cinnabarinus, AND AS AN INSECTICIDE FOR Trialeurodes vaporariorum INSTITUTO DE INVESTIGACIONES AGROPECUARIAS (INIA) (CL) 2012-03-22 US claimed
US-6133313-A SPECIFIED AVOCADOFURANS SUCH AS 2-(TETRADECYL)FURAN, 2-(PENTADECYL)FURAN, 2-(HEXADECYL)FURAN, 2-(HEPTADECYL)FURAN, 2-(OCTADECYL)FURAN, 2-(1E-PENTADECENYL)FURAN, DERIVED FROM IDIOBLAST OIL CELLS OF AVOCADO; CONTROLLING SPODOPTERA EXIGUA THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-10-17 US claimed
US-20250051687-A1 MALONATE AND FURAN BASED SURFACTANTS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2025-02-13 US disclosed
EP-4433465-A1 MALONATE AND FURAN BASED SURFACTANTS Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO (NL) 2024-09-25 EP disclosed
US-11833129-B2 Thiophene compound for treatment of exfoliating glaucoma AVOSCIENCE, LLC (US) 2023-12-05 US disclosed
CN-108602791-B Aromatic surfactants 明尼苏达大学评议会 2023-07-14 CN disclosed
WO-2023091017-A1 MALONATE AND FURAN BASED SURFACTANTS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2023-05-25 WO disclosed
WO-2023091017-A1 MALONATE AND FURAN BASED SURFACTANTS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2023-05-25 WO disclosed
US-11602518-B2 Lipidic furan, pyrrole, and thiophene compounds for use in the treatment of atrophic vaginitis AVOSCIENCE, LLC (US) 2023-03-14 US disclosed
US-11236057-B2 Aromatic surfactants REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2022-02-01 US disclosed
US-11236057-B2 Aromatic surfactants REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2022-02-01 US disclosed
US-20140309274-A1 Lipidic Furan, Pyrrole, and Thiophene Compounds for Treatment of Cancer, Neurological Disorders, and Fibrotic Disorders AVOSCIENCE, LLC (US) 2014-10-16 US disclosed
WO-2014160940-A2 LIPIDIC FURAN, PYRROLE, AND THIOPHENE COMPOUNDS FOR TREATMENT OF CANCER, NEUROLOGICAL DISORDERS, AND FIBROTIC DISORDERS AVOSCIENCE, LLC (US) 2014-10-02 WO disclosed
US-20120071551-A1 ETHANOLIC EXTRACTS OF HASS AVOCADO SEEDS, Persea americana Mill., AND ITS USE AS MITICIDE FOR Panonychus citri, Oligonychus yothersi, AND Tetranychus cinnabarinus, AND AS AN INSECTICIDE FOR Trialeurodes vaporariorum INSTITUTO DE INVESTIGACIONES AGROPECUARIAS (INIA) (CL) 2012-03-22 US disclosed
US-20120071551-A1 ETHANOLIC EXTRACTS OF HASS AVOCADO SEEDS, Persea americana Mill., AND ITS USE AS MITICIDE FOR Panonychus citri, Oligonychus yothersi, AND Tetranychus cinnabarinus, AND AS AN INSECTICIDE FOR Trialeurodes vaporariorum INSTITUTO DE INVESTIGACIONES AGROPECUARIAS (INIA) (CL) 2012-03-22 US disclosed
US-6133313-A SPECIFIED AVOCADOFURANS SUCH AS 2-(TETRADECYL)FURAN, 2-(PENTADECYL)FURAN, 2-(HEXADECYL)FURAN, 2-(HEPTADECYL)FURAN, 2-(OCTADECYL)FURAN, 2-(1E-PENTADECENYL)FURAN, DERIVED FROM IDIOBLAST OIL CELLS OF AVOCADO; CONTROLLING SPODOPTERA EXIGUA THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-10-17 US disclosed
US-6133313-A SPECIFIED AVOCADOFURANS SUCH AS 2-(TETRADECYL)FURAN, 2-(PENTADECYL)FURAN, 2-(HEXADECYL)FURAN, 2-(HEPTADECYL)FURAN, 2-(OCTADECYL)FURAN, 2-(1E-PENTADECENYL)FURAN, DERIVED FROM IDIOBLAST OIL CELLS OF AVOCADO; CONTROLLING SPODOPTERA EXIGUA THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-10-17 US disclosed
EP-0140322-B1 POLYMER CATALYST TRANSDUCERS AND USE THEREOF IN TEST KITS FOR ANALYTICAL METHODS MILES INC. (US) 1989-01-25 EP disclosed
US-4560534-A Polymer catalyst transducers MILES LABORATORIES, INC. (US) 1985-12-24 US disclosed
EP-0140322-A2 Polymer catalyst transducers and use thereof in test kits for analytical methods MILES INC. (US) 1985-05-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140309274-A1 Lipidic Furan, Pyrrole, and Thiophene Compounds for Treatment of Cancer, Neurological Disorders, and Fibrotic Disorders FAH, PHOSPHO1, FAP ALDH1A1 354/4885HPGD 637/4885CYP3A4 1039/4885
US-11236057-B2 Aromatic surfactants ALK, ABCB4, APOB ALDH1A1 1320/4885HPGD 4689/4885CYP3A4 1203/4885
US-11833129-B2 Thiophene compound for treatment of exfoliating glaucoma TYMP, TDP1, TDP2 ALDH1A1 895/4885HPGD 420/4885CYP3A4 513/4885
US-11602518-B2 Lipidic furan, pyrrole, and thiophene compounds for use in the treatment of atrophic vaginitis LPXN, PGR, CYP19A1 ALDH1A1 1266/4885HPGD 144/4885CYP3A4 403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.