SCHEMBL774982

SCHEMBL774982

C=C(C)C(=O)OCC(=O)N1CCC1=O

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
CASP6 P55212 1/20 0.41
POLB P06746 2/20 0.40
LMNA P02545 1/20 0.40
RAB9A P51151 2/20 0.39
KMT2A Q03164 3/20 0.37
ATM Q13315 1/20 0.37
TSHR P16473 3/20 0.37
ALDH1A1 P00352 1/20 0.37
THRB P10828 1/20 0.35
MAPT P10636 2/20 0.34
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL775129 0.91 LMNA (0.53) TDP1L3MBTL1CASP6POLBLMNA
SCHEMBL775270 0.89 LMNA (0.47) TDP1L3MBTL1CASP6POLBLMNA
SCHEMBL775136 0.88 TDP1 (0.46) TDP1L3MBTL1CASP6POLBLMNA
SCHEMBL775271 0.75 TDP1 (0.41) TDP1L3MBTL1CASP6POLBLMNA
SCHEMBL775293 0.75 ALDH1A1 (0.39) TDP1L3MBTL1CASP6KMT2AATM
SCHEMBL9917060 0.73 TSHR (0.36) KMT2AATMTSHRALDH1A1THRB
SCHEMBL774859 0.73 ALDH1A1 (0.36) KMT2AATMTSHRALDH1A1THRB
SCHEMBL9916019 0.72 THRB (0.37) KMT2AATMTSHRALDH1A1THRB
SCHEMBL775143 0.72 ALDH1A1 (0.38) TDP1POLBKMT2AATMTSHR
SCHEMBL775400 0.72 ALDH1A1 (0.39) KMT2AATMTSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120070778-A1 RESIN, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-22 US disclosed
US-20120070778-A1 RESIN, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-22 US disclosed