Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL775143 | 0.74 | ALDH1A1 (0.38) | TSHRALDH1A1THRBKMT2AATM | |
| SCHEMBL774982 | 0.73 | TDP1 (0.41) | TSHRALDH1A1THRBKMT2AATM | |
| SCHEMBL9916019 | 0.71 | THRB (0.37) | TSHRALDH1A1THRBKMT2AATM | |
| SCHEMBL775129 | 0.71 | LMNA (0.53) | ALDH1A1THRBKMT2A | |
| SCHEMBL7719984 | 0.70 | THRB (0.42) | TSHRALDH1A1THRBKMT2AATM | |
| SCHEMBL774997 | 0.70 | ALDH1A1 (0.38) | TSHRALDH1A1KMT2AATM | |
| SCHEMBL775270 | 0.70 | LMNA (0.47) | ALDH1A1KMT2A | |
| SCHEMBL775151 | 0.70 | ALDH1A1 (0.37) | TSHRALDH1A1THRBKMT2AATM | |
| SCHEMBL775398 | 0.70 | ALDH1A1 (0.37) | TSHRALDH1A1THRBKMT2AATM | |
| SCHEMBL774846 | 0.69 | ALDH1A1 (0.37) | TSHRALDH1A1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120148954-A1 | N-ACYL-B-LACTAM DERIVATIVE, MACROMOLECULAR COMPOUND, AND PHOTORESIST COMPOSITION | KURARAY CO., LTD. (JP) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120148954-A1 | N-ACYL-B-LACTAM DERIVATIVE, MACROMOLECULAR COMPOUND, AND PHOTORESIST COMPOSITION | COASY, ARCN1, CLTB | TSHR 3318/4885ALDH1A1 3234/4885THRB 2398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.