Sugi Predict

Sugi Predict / Compounds / SCHEMBL775093

SCHEMBL775093

SCHEMBL775093

COc1cc(-c2oc3ccc(OC)c(OC)c3c(=O)c2OC)c(OC)c(OC)c1OC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MGAM O43451 2/20 0.53
▸ ABCG2 Q9UNQ0 6/20 0.51
▸ ABCB1 P08183 4/20 0.51
▸ ADORA3 P0DMS8 3/20 0.51
▸ MAOA P21397 1/20 0.49
▸ MEN1 O00255 3/20 0.48
▸ KMT2A Q03164 3/20 0.48
▸ POLB P06746 1/20 0.48
▸ MAPT P10636 1/20 0.48
▸ KDM4E B2RXH2 3/20 0.47
▸ CYP3A4 P08684 3/20 0.47
▸ ALDH1A1 P00352 2/20 0.47
▸ MAPK1 P28482 2/20 0.47
▸ CYP2C9 P11712 2/20 0.47
▸ HSD17B10 Q99714 2/20 0.47
▸ ABCC1 P33527 1/20 0.47
▸ TDP1 Q9NUW8 1/20 0.47
▸ SLC22A2 O15244 1/20 0.46
▸ SLC22A1 O15245 1/20 0.46
▸ TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL718718 0.85 KDM4E (0.54) ABCG2ABCB1ADORA3MAOAMEN1
SCHEMBL5135081 0.82 MGAM (0.51) MGAMABCG2ABCB1ADORA3MAOA
SCHEMBL16894621 0.81 ABCG2 (0.73) ABCG2ABCB1ADORA3MAOAMEN1
SCHEMBL31182979 0.79 ABCG2 (0.55) ABCG2ABCB1ADORA3MAOAMEN1
SCHEMBL19347141 0.79 ABCG2 (0.72) ABCG2ABCB1MEN1KMT2APOLB
SCHEMBL16894634 0.79 ABCB1 (0.51) MGAMABCG2ABCB1ADORA3MEN1
SCHEMBL1764660 0.78 KDM4E (0.56) ABCG2ABCB1ADORA3MAOAMEN1
SCHEMBL1765292 0.77 ADORA3 (0.67) ABCG2ABCB1ADORA3MEN1KMT2A
SCHEMBL15514327 0.77 MAPT (0.53) MGAMABCG2ABCB1MEN1KMT2A
SCHEMBL5135083 0.76 ABCG2 (0.65) MGAMABCG2ABCB1ADORA3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 317 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250145581-A1 PURIFICATION PROCESS FOR POLYMETHOXYLATED FLAVONOIDS AND COMPOSITIONS OBTAINED THEREFROM FIRMENICH SA (CH) 2025-05-08 — — US claimed
US-20250032446-A1 METHODS AND COMPOSITIONS FOR THE BIOSYNTHESIS AND USE OF DEMETHYLATED POLYMETHOXY FLAVONES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2025-01-30 — — US claimed
US-20240397987-A1 COMPOSITION DERIVED FROM CITRUS FRUIT AND BEVERAGE CONTAINING THE SAME SUNTORY HOLDINGS LIMITED (JP) 2024-12-05 — — US claimed
EP-4440334-A1 PURIFICATION PROCESS FOR POLYMETHOXYLATED FLAVONOIDS AND COMPOSITIONS OBTAINED THEREFROM Firmenich SA (CH) 2024-10-09 — — EP claimed
EP-4415560-A1 COMPOSITION DERIVED FROM CITRUS FRUIT AND BEVERAGE CONTAINING THE SAME Suntory Holdings Limited (JP) 2024-08-21 — — EP claimed
CN-118311172-A Quick identification method for shaddock variety 华南农业大学 2024-07-09 — — CN claimed
US-20240188613-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED 2024-06-13 — — US claimed
CN-118102887-A Composition derived from citrus fruit and beverage containing the same 三得利控股株式会社 2024-05-28 — — CN claimed
US-20240090547-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED 2024-03-21 — — US claimed
US-20240065302-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED 2024-02-29 — — US claimed
US-7108887-B2 Juice processing incorporating resin treatment TROPICANA PRODUCTS, INC. (US) 2006-09-19 — — US claimed
US-20060105089-A1 Byproduct from extracting citrus juice from whole fruit is made into a slurry and extracted to provide a rudimentary peel juice, processed into a raw peel juice and microfiltered to prepare a clarified raw peel juice; peel juice is processed to remove naturally occurring components, less bitter TROPICANA PRODUCTS, INC. 2006-05-18 — — US claimed
CN-1688212-A Juice processing incorporating resin treatment TROPICANA PROD INC (US) 2005-10-26 — — CN claimed
EP-1545246-A1 JUICE PROCESSING INCORPORATING RESIN TREATMENT TROPICANA PRODUCTS, INC. (US) 2005-06-29 — — EP claimed
US-20040152641-A1 Use of polymethoxylated flavones for treating insulin resistance KGK SYNERGIZE INC. (CA) 2004-08-05 — — US claimed
WO-2004021806-A1 JUICE PROCESSING INCORPORATING RESIN TREATMENT TROPICANA PRODUCTS, INC. (US) 2004-03-18 — — WO claimed
CN-1436528-A Anticancer medicine composition of citrus multimethoxy flavone and its prepn NANJING KAOYOU SCIENCE & TRADE (CN) 2003-08-20 — — CN claimed
US-20030064144-A1 Juice processing incorporating resin treatment TROPICANA PRODUCTS, INC. 2003-04-03 — — US claimed
WO-2002087567-A2 POLYMETHOXYLATED FLAVONES FOR TREATING INSULIN RESISTANCE KGK SYNERGIZE INC. (CA) 2002-11-07 — — WO claimed
EP-0233105-A1 Therapeutical compositions based on 3-alkoxyflavone derivatives and derivatives of 3-alkoxyflavones INSTITUT PASTEUR (FR) 1987-08-19 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250032446-A1 METHODS AND COMPOSITIONS FOR THE BIOSYNTHESIS AND USE OF DEMETHYLATED POLYMETHOXY FLAVONES CYP51A1, CYP46A1, ERG28 MGAM 78/4885ABCG2 2746/4885ABCB1 2853/4885
US-20250145581-A1 PURIFICATION PROCESS FOR POLYMETHOXYLATED FLAVONOIDS AND COMPOSITIONS OBTAINED THEREFROM TAS2R40, TAS2R60, TAS2R45 MGAM 942/4885ABCG2 2402/4885ABCB1 4489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.