Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896814 | 0.82 | TYR (0.43) | TDP1ALDH1A1PTGS2TSHR | |
| SCHEMBL5125916 | 0.72 | — | — | |
| SCHEMBL3846079 | 0.70 | ALDH1A1 (0.39) | TP53TDP1ALDH1A1TRPA1HDAC8 | |
| SCHEMBL677008 | 0.70 | LMNA (0.37) | TP53TDP1ALDH1A1TRPA1HDAC8 | |
| SCHEMBL1776424 | 0.70 | TRPA1 (0.35) | TDP1TRPA1 | |
| SCHEMBL21268353 | 0.69 | ALDH1A1 (0.40) | ALDH1A1HDAC8TSHR | |
| SCHEMBL6300144 | 0.68 | — | — | |
| SCHEMBL10612043 | 0.68 | ESR1 (0.31) | ALDH1A1TRPA1TSHR | |
| SCHEMBL207542 | 0.68 | GABRA1 (0.32) | ALDH1A1 | |
| SCHEMBL1418811 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071660-A1 | N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE | Novartis AG (CH) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999043644-A1 | N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE___________________ | NOVARTIS AG (CH) | 1999-09-02 | — | — | WO | disclosed |