SCHEMBL7758404

SCHEMBL7758404

N#Cc1ccc(N(C(N)=O)C(=O)c2c(Cl)cccc2Cl)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 1/20 0.50
TAS1R1 Q7RTX1 1/20 0.50
TAS1R2 Q8TE23 1/20 0.50
GPBAR1 Q8TDU6 1/20 0.41
ALDH1A1 P00352 1/20 0.36
MEN1 O00255 1/20 0.35
NPC1 O15118 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP11B1 P15538 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
TSHR P16473 1/20 0.35
HTT P42858 1/20 0.35
NLRP3 Q96P20 1/20 0.35
PARP15 Q460N3 1/20 0.35
PARP10 Q53GL7 1/20 0.35
PARP2 Q9UGN5 1/20 0.35
MMP2 P08253 1/20 0.35
CASP1 P29466 1/20 0.35
MAPK9 P45984 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29034051 0.88 TAS1R3 (0.41) TAS1R3TAS1R1TAS1R2GPBAR1ALDH1A1
SCHEMBL28500692 0.83 ALDH1A1 (0.41) GPBAR1ALDH1A1NPC1MAPTGAA
SCHEMBL28904678 0.82 POLB (0.44) GPBAR1ALDH1A1MEN1KMT2AMAPT
SCHEMBL7754454 0.81 ALDH1A1 (0.39) GPBAR1ALDH1A1MEN1NPC1KMT2A
SCHEMBL7759289 0.81 ALDH1A1 (0.39) GPBAR1ALDH1A1MEN1NPC1KMT2A
SCHEMBL7760759 0.79 MEN1 (0.41) ALDH1A1MEN1NPC1KMT2ALMNA
SCHEMBL28500688 0.78 RORC (0.39) GPBAR1ALDH1A1MEN1KMT2ALMNA
SCHEMBL7758399 0.77 RAB9A (0.45) GPBAR1ALDH1A1MEN1NPC1KMT2A
SCHEMBL7758363 0.77 TLR7 (0.42) GPBAR1ALDH1A1MEN1KMT2ACYP11B1
SCHEMBL7758398 0.77 GPBAR1 (0.42) GPBAR1ALDH1A1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN claimed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO claimed
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN disclosed