SCHEMBL7754772

SCHEMBL7754772

O=S(=O)(CCCl)c1cc[c]cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
CA2 P00918 4/20 0.35
TP53 P04637 1/20 0.34
HSD11B1 P28845 2/20 0.32
PSIP1 O75475 1/20 0.32
PLCG1 P19174 1/20 0.31
KMT2A Q03164 4/20 0.31
MEN1 O00255 2/20 0.31
HTT P42858 2/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
NPSR1 Q6W5P4 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4365964 0.78 CA2 (0.39) ALDH1A1CYP3A4CYP2C9CYP2C19CA2
SCHEMBL1960675 0.78 ALDH1A1 (0.42) ALDH1A1CYP3A4CYP2C9CYP2C19CA2
SCHEMBL1962068 0.78 CA2 (0.59) ALDH1A1CYP3A4CYP2C9CYP2C19CA2
SCHEMBL798585 0.77 PSIP1 (0.56) ALDH1A1CA2HSD11B1PSIP1KMT2A
SCHEMBL9771535 0.77 CA2 (0.38) ALDH1A1CYP3A4CYP2C9CYP2C19CA2
SCHEMBL7863515 0.76 HSD11B1 (0.33) ALDH1A1HSD11B1PSIP1L3MBTL1
SCHEMBL426162 0.76 ALDH1A1 (0.52) ALDH1A1CYP3A4CYP2C9CYP2C19CA2
SCHEMBL3196071 0.75 ALDH1A1 (0.48) ALDH1A1CYP3A4CYP2C9CYP2C19CA2
SCHEMBL1376044 0.75
SCHEMBL159760 0.75 PSIP1 (0.58) ALDH1A1CYP3A4CYP2C9CYP2C19CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013018057-A2 FIBRE REACTIVE BISAZO REACTIVE COLORANTS, MIXTURES OF REACTIVE COLORANTS, PRODUCTION AND USE THEREOF COLOURTEX INDUSTRIES LIMITED (IN) 2013-02-07 WO disclosed
EP-0681008-B1 Black mixtures of reactive azo dyes and their use for dyeing fibrous material containing hydroxy and/or carbonamide groups DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-02-14 EP disclosed
EP-0629666-B1 Water-soluble azo compounds, process for their preparation and their use as dyestuffs DYSTAR TEXTILFARBEN GMBH & CO (DE) 1998-12-02 EP disclosed
US-5548072-A FOR WOOL, POLYAMIDES, CELLULOSE AND COTTON HOECHST AKTIENGESELLSCHAFT (DE) 1996-08-20 US disclosed
EP-0629666-A1 Water-soluble azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1994-12-21 EP disclosed
US-4644058-A FOR CELLULOSE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-02-17 US disclosed
EP-0080352-B1 REACTIVE DYE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-11-12 EP disclosed
EP-0080352-A2 Reactive dye SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-06-01 EP disclosed