Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.59 |
| ▸ | LOX | P28300 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325260 | 0.84 | CA2 (0.78) | CA2LOXPOLBALDH1A1CYP3A4 | |
| SCHEMBL9771535 | 0.81 | CA2 (0.38) | CA2POLBALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL1960675 | 0.78 | ALDH1A1 (0.42) | CA2ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4365964 | 0.78 | CA2 (0.39) | CA2LOXALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL7754772 | 0.78 | ALDH1A1 (0.38) | CA2POLBALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL2454945 | 0.77 | CA2 (0.63) | CA2POLBALDH1A1TP53HSD11B1 | |
| SCHEMBL10792219 | 0.77 | CA2 (0.69) | CA2LOXPOLBALDH1A1CYP3A4 | |
| SCHEMBL4524280 | 0.76 | CA2 (0.47) | CA2LOXPOLBALDH1A1HSD11B1 | |
| SCHEMBL8022461 | 0.76 | CA2 (0.35) | CA2POLBALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL4611003 | 0.76 | CA2 (0.35) | CA2LOXALDH1A1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745474-B2 | Acid dyes, process for the production thereof and their use | DYSTAR COLOURS DISTRIBUTION GMBH (DE) | 2017-08-29 | — | — | US | claimed |
| EP-3063232-B1 | ACID DYES, PROCESS FOR THE PRODUCTION THEREOF AND THEIR USE | DYSTAR COLOURS DISTRIB GMBH (DE) | 2017-05-17 | — | — | EP | claimed |
| US-9650516-B2 | Acid dyes, process for the production thereof and their use | DYSTAR COLOURS DISTRIBUTION GMBH (DE) | 2017-05-16 | — | — | US | claimed |
| EP-3063229-B1 | ACID DYES, PROCESS FOR THEIR PRODUCTION AND THEIR USE | DYSTAR COLOURS DISTRIB GMBH (DE) | 2016-12-14 | — | — | EP | claimed |
| US-20160264783-A1 | ACID DYES, PROCESS FOR THE PRODUCTION THEREOF AND THEIR USE | DYSTAR COLOURS DISTRIBUTION GMBH (DE) | 2016-09-15 | — | — | US | claimed |
| US-20160257816-A1 | ACID DYES, PROCESS FOR THE PRODUCTION THEREOF AND THEIR USE | DYSTAR COLOURS DISTRIBUTION GMBH (DE) | 2016-09-08 | — | — | US | claimed |
| EP-3063229-A1 | ACID DYES, PROCESS FOR THEIR PRODUCTION AND THEIR USE | DyStar Colours Distribution GmbH (DE) | 2016-09-07 | — | — | EP | claimed |
| EP-3063232-A1 | ACID DYES, PROCESS FOR THE PRODUCTION THEREOF AND THEIR USE | DyStar Colours Distribution GmbH (DE) | 2016-09-07 | — | — | EP | claimed |
| CN-105683297-A | Acid dyes, process for the production thereof and their use | 德司达染料分销有限公司 | 2016-06-15 | — | — | CN | claimed |
| CN-102686587-B | Azaindole glucokinase activators | HOFFMANN LA ROCHE | 2015-05-27 | — | — | CN | claimed |
| CN-102686587-A | Azaindole glucokinase activators | HOFFMANN LA ROCHE | 2012-09-19 | — | — | CN | claimed |
| US-8222416-B2 | Azaindole glucokinase activators | HOFFMANN-LA ROCHE INC. (US) | 2012-07-17 | — | — | US | claimed |
| WO-2011073117-A1 | AZAINDOLE GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-06-23 | — | — | WO | claimed |
| US-20110144105-A1 | AZAINDOLE GLUCOKINASE ACTIVATORS | BERTHEL STEVEN JOSEPH | 2011-06-16 | — | — | US | claimed |
| EP-2059517-A1 | PYRIMIDINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | Biovitrum AB (publ) (SE) | 2009-05-20 | — | — | EP | claimed |
| EP-2059516-A1 | PYRIDINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (publ) (SE) | 2009-05-20 | — | — | EP | claimed |
| US-20080103141-A1 | New compounds | BIOVITRUM (SE) | 2008-05-01 | — | — | US | claimed |
| US-20080103123-A1 | New compounds | BIOVITRUM (SE) | 2008-05-01 | — | — | US | claimed |
| WO-2008025798-A1 | PYRIDINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2008-03-06 | — | — | WO | claimed |
| WO-2008025800-A1 | PYRIMIDINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2008-03-06 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144105-A1 | AZAINDOLE GLUCOKINASE ACTIVATORS | GCK, GCKR, GALK1 | CA2 2297/4885LOX 1669/4885POLB 3362/4885 |
| US-20080103141-A1 | New compounds | GPR119, GPR3, GPR4 | CA2 1140/4885LOX 3758/4885POLB 4644/4885 |
| US-20080103123-A1 | New compounds | GPR119, GPR139, GPR180 | CA2 1045/4885LOX 3760/4885POLB 4633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.