Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5158566 | 0.68 | ALDH1A1 (0.46) | G6PDIDESMN1; SMN2ENPP2PTGS2 | |
| SCHEMBL17948135 | 0.65 | PKM (0.53) | BRD4G6PDIDESMN1; SMN2ENPP2 | |
| SCHEMBL27473342 | 0.63 | MEN1 (0.40) | BRD4G6PDIDESMN1; SMN2ENPP2 | |
| SCHEMBL758951 | 0.62 | LMNA (0.64) | G6PDIDESMN1; SMN2ENPP2PTGS2 | |
| SCHEMBL11685503 | 0.62 | PTGS2 (0.39) | BRD4G6PDIDESMN1; SMN2PTGS2 | |
| SCHEMBL2376239 | 0.62 | ENPP2 (0.72) | ENPP2PTGS2 | |
| SCHEMBL12508320 | 0.61 | AKR1C3 (0.58) | G6PDIDESMN1; SMN2ENPP2PTGS2 | |
| SCHEMBL16574199 | 0.61 | PTGS2 (0.61) | PTGS2PTGDR2 | |
| SCHEMBL7125518 | 0.61 | PARG (0.59) | SMN1; SMN2PTGS2LMNA | |
| SCHEMBL13203351 | 0.60 | AKR1C3 (0.52) | G6PDIDESMN1; SMN2ENPP2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073407-A1 | HAIR DYEING METHOD USING AN ALIPHATIC CATIONIC AMINE AND A ALDEHYDE OR KETONE ORQUINONE OR DI-IMINO-ISOINDOLINE OR 3-AMINO-ISO-INDOLONE DERIVATIVES | L'OREAL (FR) | 2001-02-07 | — | — | EP | disclosed |
| WO-2000038640-A1 | HAIR DYEING METHOD USING AN ALIPHATIC CATIONIC AMINE AND A ALDEHYDE OR KETONE OR QUINONE OR DI-IMINO-ISOINDOLINE OR 3-AMINO-ISO-INDOLONE DERIVATIVES | L'OREAL (FR) | 2000-07-06 | — | — | WO | disclosed |