SCHEMBL7125518

SCHEMBL7125518

CS(=O)(=O)c1ccc2c(c1)C(=O)c1ccccc1C2=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARG Q86W56 6/20 0.59
SMN1; SMN2 Q16637 4/20 0.56
MAPK1 P28482 4/20 0.56
KMT2A Q03164 4/20 0.56
MEN1 O00255 3/20 0.56
MAPT P10636 3/20 0.56
HTT P42858 2/20 0.56
PKM P14618 1/20 0.56
ELANE P08246 1/20 0.55
PTGS2 P35354 3/20 0.52
NPC1 O15118 3/20 0.50
ALDH1A1 P00352 3/20 0.50
RAB9A P51151 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
LMNA P02545 1/20 0.50
PLA2G1B P04054 1/20 0.50
NFKB1 P19838 1/20 0.50
CASP3 P42574 1/20 0.50
NFKB2 Q00653 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9239718 0.90 PTGS2 (0.59) PARGSMN1; SMN2MAPK1KMT2AMEN1
SCHEMBL9416577 0.90 PTGS2 (0.59) PARGSMN1; SMN2MAPK1KMT2AMEN1
SCHEMBL17948135 0.89 PKM (0.53) PARGSMN1; SMN2MAPK1KMT2AMEN1
SCHEMBL10070529 0.84 PARG (0.44) PARGSMN1; SMN2MAPK1KMT2AMEN1
SCHEMBL27567614 0.83 KMT2A (0.59) PARGSMN1; SMN2MAPK1KMT2AMEN1
SCHEMBL11085074 0.80 ESR1 (0.62) PARGSMN1; SMN2KMT2AMEN1MAPT
SCHEMBL13568738 0.79 PKLR (0.44) PARGSMN1; SMN2MAPK1KMT2AMEN1
Potassium Ion SCHEMBL2784885 0.79 PARG (0.59) PARGSMN1; SMN2MAPK1KMT2AMEN1
SCHEMBL919135 0.79 KMT2A (0.56) PARGSMN1; SMN2MAPK1KMT2AMEN1
SCHEMBL426122 0.79 KMT2A (0.56) PARGSMN1; SMN2MAPK1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170043931-A1 USE OF PROTECTED N-HYDROXYIMIDE DERIVATES AND TRANSITION METAL AS OXYGEN SCAVENGER SYSTEM IN TRANSPARENT POLYOLEFIN FILMS BASF SE (DE) 2017-02-16 US disclosed
US-20170043931-A1 USE OF PROTECTED N-HYDROXYIMIDE DERIVATES AND TRANSITION METAL AS OXYGEN SCAVENGER SYSTEM IN TRANSPARENT POLYOLEFIN FILMS BASF SE (DE) 2017-02-16 US disclosed
US-9505541-B2 Use of protected N-hydroxyimide derivates and transition metal as oxygen scavenger system in transparent polyolefin films BASF SE (DE) 2016-11-29 US disclosed
US-9505541-B2 Use of protected N-hydroxyimide derivates and transition metal as oxygen scavenger system in transparent polyolefin films BASF SE (DE) 2016-11-29 US disclosed
US-20150217923-A1 USE OF PROTECTED N-HYDROXYIMIDE DERIVATES AND TRANSITION METAL AS OXYGEN SCAVENGER SYSTEM IN TRANSPARENT POLYOLEFIN FILMS BASF SE (DE) 2015-08-06 US disclosed
US-20150217923-A1 USE OF PROTECTED N-HYDROXYIMIDE DERIVATES AND TRANSITION METAL AS OXYGEN SCAVENGER SYSTEM IN TRANSPARENT POLYOLEFIN FILMS BASF SE (DE) 2015-08-06 US disclosed
US-20140086936-A1 MATRIPTASE INHIBITORS AND USES THEREOF AGAINST ORTHOMYXOVIRIDAE INFECTIONS SOCPRA Sciences Sante et Humaines S.E.C. (CA) 2014-03-27 US disclosed
US-20130023609-A1 Use of protected N-hydroxyimide derivates and transition metal as oxygen scavenger system in transparent polyolefin films BASF SE (DE) 2013-01-24 US disclosed
US-20130023609-A1 Use of protected N-hydroxyimide derivates and transition metal as oxygen scavenger system in transparent polyolefin films BASF SE (DE) 2013-01-24 US disclosed
WO-2011067197-A2 USE OF PROTECTED N-HYDROXYIMIDE DERIVATES AND TRANSITION METAL AS OXYGEN SCAVENGER SYSTEM IN TRANSPARENT POLYOLEFIN FILMS BASF SE (DE) 2011-06-09 WO disclosed
US-20090286060-A1 Degradable polymer article CIBA CORP. 2009-11-19 US disclosed
US-20090286060-A1 Degradable polymer article CIBA CORP. 2009-11-19 US disclosed
WO-2007028731-A1 A DEGRADABLE POLYMER ARTICLE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2007-03-15 WO disclosed
JP-2003212840-A METHOD FOR PRODUCING 2- TRIBROMOMETHYLSULFONYLANTHRAQUINONE SUMITOMO SEIKA CHEM CO LTD 2003-07-30 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140086936-A1 MATRIPTASE INHIBITORS AND USES THEREOF AGAINST ORTHOMYXOVIRIDAE INFECTIONS MMP7, MATR3, ADAMTS1 PARG 2622/4885SMN1; SMN2 2353/4885MAPK1 734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.