SCHEMBL7755344

SCHEMBL7755344

CC1=CC(=O)N(CC(C)C)C1=O

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 2/20 0.36
MPO P05164 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
ALDH1A1 P00352 5/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
GAA P10253 3/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
TOP2A P11388 1/20 0.33
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PIK3CD O00329 1/20 0.32
LMNA P02545 1/20 0.32
MAPK1 P28482 1/20 0.32
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19301853 0.84 PTGS1 (0.36)
SCHEMBL15977378 0.82 EP300 (0.35) EP300MPOMEN1KMT2AALDH1A1
SCHEMBL8886547 0.82 KMT2A (0.40) MEN1KMT2AALDH1A1RAB9ATSHR
SCHEMBL24939870 0.80 APAF1 (0.41) ALDH1A1LMNA
SCHEMBL11805906 0.78 XPO1 (0.33) ALDH1A1LMNAMAPT
SCHEMBL4395914 0.78 MGLL (0.33) ALDH1A1NPC1RAB9ATSHRSMN1; SMN2
SCHEMBL9064643 0.77 KMT2A (0.37) KMT2AALDH1A1RAB9ASMN1; SMN2LMNA
SCHEMBL8439401 0.77 TERT (0.32) MEN1KMT2AALDH1A1NPC1RAB9A
SCHEMBL8443693 0.77 DAO (0.43) KMT2AALDH1A1L3MBTL1
SCHEMBL14578297 0.76 MGLL (0.33) MEN1KMT2AALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018298-A1 OLEFINIC COMPOSITIONS COMPRISING HYDROCARBON RESINS ExxonMobil Product Solutions Company 2024-01-18 US disclosed
US-20220025446-A1 METHODS OF USING MASTER / COPY ARRAYS FOR SPATIAL DETECTION 10X GENOMICS, INC. (US) 2022-01-27 US disclosed
US-11008596-B2 Cytochrome P450 BM3 enzyme variants for preparation of cyclopropanes CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2021-05-18 US disclosed
EP-3464310-B1 TAGGED MULTI-NUCLEOTIDES USEFUL FOR NUCLEIC ACID SEQUENCING HOFFMANN LA ROCHE (CH) 2021-01-27 EP disclosed
US-20190211367-A1 VIVO AND IN VITRO OLEFIN CYCLOPROPANATION CATALYZED BY HEME ENZYMES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2019-07-11 US disclosed
US-10208322-B2 In vivo and in vitro olefin cyclopropanation catalyzed by heme enzymes CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2019-02-19 US disclosed
US-20170247725-A1 IN VIVO AND IN VITRO OLEFIN CYCLOPROPANATION CATALYZED BY HEME ENZYMES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2017-08-31 US disclosed
CN-103113279-A Maleimide type compound, as well as preparation and application thereof UNIV ZHEJIANG TECHNOLOGY 2013-05-22 CN disclosed
EP-0723967-B1 Organometallic compounds and polymers made therefrom ATOCHEM NORTH AMERICA ELF (US) 2001-04-11 EP disclosed
US-5786392-A SUSTAINED RELEASE; MARINE ANTIFOULING AGENT ATOFINA CHEMICALS, INC., A CORP. OF PENNSYLVANIA 1998-07-28 US disclosed
US-5637745-A MARINE ANTIFOULING AGENT; SUSTAINED RELEASE ELF ATOCHEM NORTH AMERICA, INC. (US) 1997-06-10 US disclosed
EP-0723967-A1 Organometallic compounds and polymers made therefrom ELF ATOCHEM NORTH AMERICA, INC. (US) 1996-07-31 EP disclosed