Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8886547 | 0.91 | KMT2A (0.40) | KMT2ASMN1; SMN2LMNAMAPK1ALDH1A1 | |
| SCHEMBL4848834 | 0.79 | RGS4 (0.45) | POLBSMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL7755344 | 0.77 | EP300 (0.36) | KMT2ASMN1; SMN2LMNAMAPK1ALDH1A1 | |
| SCHEMBL14377608 | 0.75 | ALDH1A1 (0.41) | KMT2APOLBSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL19301853 | 0.74 | PTGS1 (0.36) | — | |
| SCHEMBL24939870 | 0.74 | APAF1 (0.41) | POLBLMNAALDH1A1 | |
| SCHEMBL2464170 | 0.73 | KDM4E (0.43) | KMT2APOLBSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL1398263 | 0.72 | MGLL (0.41) | POLBSMN1; SMN2LMNAMAPK1ALDH1A1 | |
| SCHEMBL24939866 | 0.72 | APAF1 (0.31) | POLBLMNAALDH1A1MAPT | |
| SCHEMBL11805906 | 0.72 | XPO1 (0.33) | LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523360-A | IMPROVES MELT-FLOW PROPERTIES | AKZO NOBEL N. V. (NL) | 1996-06-04 | — | — | US | disclosed |
| EP-0648240-A1 | PROCESS FOR THE MODIFICATION OF POLYPHENYLENE ETHER RESIN COMPOSITIONS | Akzo Nobel N.V. (NL) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994001485-A1 | PROCESS FOR THE MODIFICATION OF POLYPHENYLENE ETHER RESIN COMPOSITIONS | AKZO NOBEL N.V. (NL) | 1994-01-20 | — | — | WO | disclosed |