Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9064643 | 0.91 | KMT2A (0.37) | KMT2AALDH1A1MAPK1MAPTRAB9A | |
| SCHEMBL7755344 | 0.82 | EP300 (0.36) | KMT2AALDH1A1MAPK1MEN1TSHR | |
| SCHEMBL19301853 | 0.78 | PTGS1 (0.36) | — | |
| SCHEMBL24939870 | 0.78 | APAF1 (0.41) | ALDH1A1PIN1PIN4LMNA | |
| SCHEMBL24939866 | 0.77 | APAF1 (0.31) | ALDH1A1MAPTPIN1PIN4LMNA | |
| SCHEMBL4395914 | 0.76 | MGLL (0.33) | ALDH1A1MAPK1TSHRMAPTRAB9A | |
| SCHEMBL11805906 | 0.76 | XPO1 (0.33) | ALDH1A1MAPTLMNA | |
| SCHEMBL4011867 | 0.74 | ALDH1A1 (0.48) | KMT2AALDH1A1MAPK1MEN1MAPT | |
| SCHEMBL22105296 | 0.73 | JUN (0.34) | — | |
| SCHEMBL2464170 | 0.73 | KDM4E (0.43) | KMT2AALDH1A1MEN1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610240-A | CITRACONIC IMIDES | AKZO NOBEL NV (NL) | 1997-03-11 | — | — | US | disclosed |
| EP-0555288-B1 | ANTI-REVERSION COAGENTS FOR RUBBER VULCANIZATION | AKZO NOBEL NV (NL) | 1996-06-19 | — | — | EP | disclosed |
| US-5426155-A | Adjuvants which prevent loss of crosslinking in vulcanized rubbers | AKZO NOBEL N.V. (NL) | 1995-06-20 | — | — | US | disclosed |
| EP-0640114-A1 | SULFUR-VULCANIZED RUBBER COMPOSITION | Akzo Nobel N.V. (NL) | 1995-03-01 | — | — | EP | disclosed |
| WO-1993023467-A1 | SULFUR-VULCANIZED RUBBER COMPOSITION | AKZO NOBEL N.V. (NL) | 1993-11-25 | — | — | WO | disclosed |