Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7220855 | 0.88 | MEP1B (0.58) | MEP1BALDH1A1AKR1C3L3MBTL1MEN1 | |
| SCHEMBL7751590 | 0.83 | MEP1B (0.53) | MEP1BALDH1A1AKR1C3L3MBTL1MEN1 | |
| SCHEMBL2678034 | 0.83 | ALDH1A1 (0.62) | MEP1BALDH1A1AKR1C3L3MBTL1MAPK1 | |
| SCHEMBL3199069 | 0.82 | ATM (0.64) | MEP1BALDH1A1AKR1C3L3MBTL1NPSR1 | |
| SCHEMBL7756193 | 0.81 | ATM (0.56) | MEP1BALDH1A1AKR1C3L3MBTL1MAPK1 | |
| SCHEMBL7219827 | 0.81 | MEP1B (0.61) | MEP1BALDH1A1AKR1C3L3MBTL1LMNA | |
| SCHEMBL3074642 | 0.81 | ALDH1A1 (0.67) | MEP1BALDH1A1AKR1C3L3MBTL1MAPK1 | |
| SCHEMBL11157739 | 0.79 | MEP1B (0.59) | MEP1BALDH1A1AKR1C3L3MBTL1KMT2A | |
| SCHEMBL29306675 | 0.79 | MEP1B (0.59) | MEP1BALDH1A1AKR1C3L3MBTL1MEN1 | |
| SCHEMBL1466020 | 0.78 | LMNA (0.63) | MEP1BALDH1A1AKR1C3L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001051126-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-07-19 | — | — | WO | disclosed |