Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | EP300 | Q09472 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7756777 | 0.94 | OPRD1 (0.52) | OPRD1ALOX5EP300PTGS2 | |
| SCHEMBL14195275 | 0.94 | ALOX5 (0.51) | OPRD1MAPK14ALOX5EP300PTGS2 | |
| SCHEMBL7761536 | 0.90 | OPRD1 (0.48) | OPRD1ALOX5EP300PTGS2 | |
| SCHEMBL678077 | 0.87 | ALOX5 (0.56) | OPRD1MAPK14ALOX5EP300PTGS2 | |
| SCHEMBL7760704 | 0.84 | OPRD1 (0.49) | OPRD1ALOX5EP300 | |
| SCHEMBL7760695 | 0.81 | OPRD1 (0.56) | OPRD1EP300PTGS2POLB | |
| SCHEMBL7902764 | 0.80 | OPRD1 (0.54) | OPRD1MAPK14EP300PTGS2 | |
| SCHEMBL7899189 | 0.79 | OPRD1 (0.51) | OPRD1MAPK14EP300 | |
| Hydrochloric Acid SCHEMBL8985503 | 0.79 | EP300 (0.44) | OPRD1MAPK14EP300PTGS2PTGS1 | |
| SCHEMBL17833490 | 0.75 | MAPK14 (0.42) | OPRD1MAPK14ALOX5EP300PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728755-B1 | Thiophene compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-04-11 | — | — | EP | claimed |
| EP-0728755-A1 | Thiophene compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-08-28 | — | — | EP | claimed |