Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | GRM6 | O15303 | 1/20 | 0.47 |
| ▸ | EP300 | Q09472 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7760695 | 0.85 | OPRD1 (0.56) | OPRD1EP300ALDH1A1MAPTHPGD | |
| SCHEMBL7756777 | 0.84 | OPRD1 (0.52) | OPRD1GRM6EP300ALDH1A1KDM4E | |
| SCHEMBL7902764 | 0.84 | OPRD1 (0.54) | OPRD1GRM6EP300ALDH1A1MAPT | |
| SCHEMBL7760704 | 0.83 | OPRD1 (0.49) | OPRD1GRM6EP300ALDH1A1MAPT | |
| SCHEMBL7761536 | 0.82 | OPRD1 (0.48) | OPRD1GRM6EP300ALDH1A1MAPT | |
| SCHEMBL678077 | 0.80 | ALOX5 (0.56) | OPRD1GRM6EP300ALDH1A1KDM4E | |
| SCHEMBL7756786 | 0.79 | OPRD1 (0.47) | OPRD1EP300MAPK14 | |
| SCHEMBL5599629 | 0.77 | OPRD1 (0.53) | OPRD1EP300ALDH1A1MAPTHPGD | |
| SCHEMBL7760717 | 0.76 | OPRD1 (0.50) | OPRD1EP300KDM4EMEN1KMT2A | |
| SCHEMBL7760707 | 0.76 | OPRD1 (0.50) | OPRD1EP300KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37078-E1 | Thiophene compounds | ADIR ET COMPAGNIE (FR) | 2001-02-27 | — | — | US | disclosed |
| US-5705525-A | ANTIINFLAMMATORY AGENTS AND TREATMENT OF RHEUMATIC DISEASES | ADIR ET COMPAGNIE (FR) | 1998-01-06 | — | — | US | disclosed |