Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7755582 | 0.90 | MTNR1A (0.51) | MTNR1AMTNR1BHTR1AHTR1DHTR2C | |
| SCHEMBL7757677 | 0.88 | MTNR1A (0.54) | MTNR1AMTNR1BHTR1AHTR1DHTR2C | |
| SCHEMBL132847 | 0.81 | MTNR1A (0.66) | MTNR1AMTNR1BHTR2CNQO2 | |
| SCHEMBL7752945 | 0.77 | HTR1A (0.58) | HTR1AHTR1DHTR2CHCRTR2MEN1 | |
| SCHEMBL8432485 | 0.74 | MTNR1A (0.61) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8574906 | 0.74 | MTNR1A (0.61) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL6076698 | 0.72 | MTNR1A (0.64) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8278122 | 0.72 | HCRTR2 (0.43) | MTNR1AHCRTR2MEN1KMT2ATP53 | |
| SCHEMBL136496 | 0.72 | MTNR1A (0.64) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL3652699 | 0.72 | MTNR1A (0.54) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721947-B1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-03-14 | — | — | EP | disclosed |
| US-5703121-A | SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-12-30 | — | — | US | disclosed |
| EP-0721947-A1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-07-17 | — | — | EP | disclosed |