Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.66 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.62 |
| ▸ | NQO2 | P16083 | 7/20 | 0.62 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3652699 | 0.90 | MTNR1A (0.54) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL5223857 | 0.88 | MTNR1A (0.72) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL136496 | 0.88 | MTNR1A (0.64) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL138000 | 0.87 | MTNR1A (0.51) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL135119 | 0.86 | MTNR1A (0.65) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7757152 | 0.81 | MTNR1A (0.50) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL7755582 | 0.80 | MTNR1A (0.51) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL7200942 | 0.80 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL9628106 | 0.79 | PPARD (0.56) | — | |
| SCHEMBL5228871 | 0.79 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120059053-A1 | COMPOUNDS OF 2,3-DIHYDRO-BENZOFURAN | FERRER INTERNATIONAL, S.A. (ES) | 2012-03-08 | — | — | US | claimed |
| EP-2205579-A1 | COMPOUNDS OF 2,3-DIHYDRO-BENZOFURAN | FERRER INTERNACIONAL, S.A. (ES) | 2010-07-14 | — | — | EP | claimed |
| WO-2009053444-A1 | COMPOUNDS OF 2,3-DIHYDRO-BENZOFURAN | FERRER INTERNACIONAL, S.A. (ES) | 2009-04-30 | — | — | WO | claimed |
| US-20120059053-A1 | COMPOUNDS OF 2,3-DIHYDRO-BENZOFURAN | FERRER INTERNATIONAL, S.A. (ES) | 2012-03-08 | — | — | US | disclosed |
| EP-2205579-A1 | COMPOUNDS OF 2,3-DIHYDRO-BENZOFURAN | FERRER INTERNACIONAL, S.A. (ES) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009053444-A1 | COMPOUNDS OF 2,3-DIHYDRO-BENZOFURAN | FERRER INTERNACIONAL, S.A. (ES) | 2009-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059053-A1 | COMPOUNDS OF 2,3-DIHYDRO-BENZOFURAN | MTNR1A, MTNR1B, CRY2 | MTNR1A 1/4885MTNR1B 2/4885NQO2 1107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.