Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.58 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30035899 | 1.00 | APOBEC3G (0.58) | APOBEC3GGABRA1GABRB2ACHEMAPT | |
| SCHEMBL9195152 | 0.89 | APOBEC3G (0.48) | APOBEC3GGABRA1GABRB2ACHEMAPT | |
| SCHEMBL9194919 | 0.89 | MGLL (0.50) | APOBEC3GGABRA1GABRB2ACHEMAPT | |
| SCHEMBL16326729 | 0.86 | APOBEC3G (0.45) | APOBEC3GGABRA1GABRB2ACHEMAPT | |
| SCHEMBL74169 | 0.84 | SLC6A2 (0.47) | APOBEC3GGABRA1GABRB2ACHE | |
| SCHEMBL9190080 | 0.84 | APOBEC3G (0.44) | APOBEC3GGABRA1GABRB2ACHEMAPT | |
| SCHEMBL8481321 | 0.82 | CHRM2 (0.50) | APOBEC3GGABRA1GABRB2ACHEMAPT | |
| SCHEMBL2034768 | 0.80 | GABRA1 (0.46) | APOBEC3GGABRA1GABRB2ACHEMAPT | |
| SCHEMBL775854 | 0.80 | GABRA1 (0.41) | APOBEC3GGABRA1GABRB2ACHEMAPT | |
| SCHEMBL943257 | 0.80 | APOBEC3G (0.54) | APOBEC3GMAPTNPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153305-A | From diaryl disulfide; mild conditions using organometallic catalyst | RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) | 1992-10-06 | — | — | US | claimed |
| US-12435061-B2 | Compounds and compositions for use in treating skin disorders | KAMARI PHARMA LTD. (IL) | 2025-10-07 | — | — | US | disclosed |
| EP-4574822-A2 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | Kamari Pharma Ltd. (IL) | 2025-06-25 | — | — | EP | disclosed |
| US-12100809-B2 | Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery | MITSUBISHI CHEMICAL CORPORATION (JP) | 2024-09-24 | — | — | US | disclosed |
| EP-4361200-A1 | METHOD FOR MANUFACTURING SULFUR-CONTAINING POLYMER | Nippon Shokubai Co., Ltd. (JP) | 2024-05-01 | — | — | EP | disclosed |
| US-20240124413-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | KAMARI PHARMA LTD. (IL) | 2024-04-18 | — | — | US | disclosed |
| CN-114989050-B | Synthesis method of symmetrical disulfide compound | 浙江大学衢州研究院 | 2023-12-29 | — | — | CN | disclosed |
| US-11807621-B2 | Compounds and compositions for use in treating skin disorders | KAMARI PHARMA LTD. (IL) | 2023-11-07 | — | — | US | disclosed |
| US-11807621-B2 | Compounds and compositions for use in treating skin disorders | KAMARI PHARMA LTD. (IL) | 2023-11-07 | — | — | US | disclosed |
| US-11807621-B2 | Compounds and compositions for use in treating skin disorders | KAMARI PHARMA LTD. (IL) | 2023-11-07 | — | — | US | disclosed |
| US-20050131012-A1 | Substituted 1H-pyrrolo[3,2-b, 3,2-c, and 2,3-c]pyridine-2-carboxamides and related analogs as inhibitors of casein kinase lepsilon | AVENTIS PHARMACEUTICALS INC. (US) | 2005-06-16 | — | — | US | disclosed |
| CN-1191283-C | Nonconjugated cyclic polyene copolymer, rubber composition, and use | MITSUI CHEMICALS INC (JP) | 2005-03-02 | — | — | CN | disclosed |
| CN-1327454-A | Unconjugated cyclopolyene copolymer, rubber composition, and use | MITSUI CHEMICALS INC (JP) | 2001-12-19 | — | — | CN | disclosed |
| EP-0402481-B1 | PRODUCTION OF POLYARYLENE THIOETHER | PROD DEV RES INST (JP) | 1995-10-25 | — | — | EP | disclosed |
| US-5290911-A | Forming polymers by catalytic oxidative coupling | RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) | 1994-03-01 | — | — | US | disclosed |
| US-5153305-A | From diaryl disulfide; mild conditions using organometallic catalyst | RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) | 1992-10-06 | — | — | US | disclosed |
| US-4983720-A | Process for preparing a polyarylene thioether | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1991-01-08 | — | — | US | disclosed |
| EP-0402481-A1 | PRODUCTION OF POLYARYLENE THIOETHER | RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) | 1990-12-19 | — | — | EP | disclosed |
| US-4931542-A | Process for preparing a polyarylene thioether | IDEMITSU PETROCHEMICAL COMPANY, LIMITED (JP) | 1990-06-05 | — | — | US | disclosed |
| EP-0281036-A2 | A process for preparing a polyarylene thioether | IDEMITSU PETROCHEMICAL CO. LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12435061-B2 | Compounds and compositions for use in treating skin disorders | RDX, HAX1, F12 | APOBEC3G 3162/4885GABRA1 4595/4885GABRB2 4575/4885 |
| US-20050131012-A1 | Substituted 1H-pyrrolo[3,2-b, 3,2-c, and 2,3-c]pyridine-2-carboxamides and related analogs as inhibitors of casein kinase lepsilon | CSNK2A3, PACSIN2, CSNK1G3 | APOBEC3G 4153/4885GABRA1 1955/4885GABRB2 1522/4885 |
| US-20240124413-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | RDX, HAX1, F12 | APOBEC3G 3162/4885GABRA1 4595/4885GABRB2 4575/4885 |
| US-11807621-B2 | Compounds and compositions for use in treating skin disorders | RDX, HAX1, F12 | APOBEC3G 3162/4885GABRA1 4595/4885GABRB2 4575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.