SCHEMBL9190080

SCHEMBL9190080

CCc1ccccc1SSc1c(C)cccc1C

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
APOBEC3G Q9HC16 1/20 0.44
GABRA1 P14867 2/20 0.38
GABRB2 P47870 2/20 0.38
LMNA P02545 2/20 0.36
PTGS2 P35354 2/20 0.36
ACHE P22303 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
SCN4A P35499 2/20 0.34
ALDH1A1 P00352 2/20 0.34
ALOX12 P18054 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MAPT P10636 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
SHBG P04278 1/20 0.33
PTGS1 P23219 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9195152 0.86 APOBEC3G (0.48) APOBEC3GGABRA1GABRB2ACHEMAPT
SCHEMBL9190039 0.85 APOBEC3G (0.39) APOBEC3GGABRA1GABRB2LMNAPTGS2
SCHEMBL9193727 0.84 GABRA1 (0.43) GABRA1GABRB2PTGS2TAAR1SCN4A
SCHEMBL775852 0.84 APOBEC3G (0.58) APOBEC3GGABRA1GABRB2ACHEMAPT
SCHEMBL30035899 0.84 APOBEC3G (0.58) APOBEC3GGABRA1GABRB2ACHEMAPT
SCHEMBL9269383 0.82 GABRA1 (0.44) GABRA1GABRB2PTGS2TAAR1SCN4A
SCHEMBL9195424 0.80 ACHE (0.41) APOBEC3GACHESCN4AALDH1A1MAPT
SCHEMBL9194919 0.75 MGLL (0.50) APOBEC3GGABRA1GABRB2LMNAACHE
SCHEMBL904832 0.75 HTR1A (0.45) LMNATAAR1ALDH1A1
SCHEMBL895629 0.74 CYP2A6 (0.47) ACHESCN4AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5153305-A From diaryl disulfide; mild conditions using organometallic catalyst RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) 1992-10-06 US claimed
EP-0402481-B1 PRODUCTION OF POLYARYLENE THIOETHER PROD DEV RES INST (JP) 1995-10-25 EP disclosed
US-5290911-A Forming polymers by catalytic oxidative coupling RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) 1994-03-01 US disclosed
US-5153305-A From diaryl disulfide; mild conditions using organometallic catalyst RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) 1992-10-06 US disclosed
US-4983720-A Process for preparing a polyarylene thioether IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1991-01-08 US disclosed
EP-0402481-A1 PRODUCTION OF POLYARYLENE THIOETHER RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) 1990-12-19 EP disclosed
US-4931542-A Process for preparing a polyarylene thioether IDEMITSU PETROCHEMICAL COMPANY, LIMITED (JP) 1990-06-05 US disclosed
EP-0281036-A2 A process for preparing a polyarylene thioether IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1988-09-07 EP disclosed