Sugi Predict

Sugi Predict / Compounds / SCHEMBL776194

SCHEMBL776194

SCHEMBL776194

COC(=O)C(C)(C)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DGAT1 O75907 1/20 0.42
▸ ALDH1A1 P00352 2/20 0.41
▸ ELANE P08246 1/20 0.34
▸ PRTN3 P24158 1/20 0.34
▸ GAA P10253 2/20 0.33
▸ KCNN4 O15554 1/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ LMNA P02545 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ PDK1 Q15118 2/20 0.32
▸ PDK2 Q15119 2/20 0.32
▸ PDK3 Q15120 2/20 0.32
▸ PDK4 Q16654 2/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ L3MBTL1 Q9Y468 2/20 0.31
▸ CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1424791 0.82 DGAT1 (0.50) DGAT1ALDH1A1ELANEGAAKCNN4
SCHEMBL11034219 0.78 DGAT1 (0.42) DGAT1ALDH1A1GAAKCNN4MEN1
SCHEMBL9722993 0.78 DGAT1 (0.42) DGAT1ALDH1A1GAAKCNN4MEN1
SCHEMBL12761004 0.78 DGAT1 (0.42) DGAT1ALDH1A1GAAKCNN4MEN1
SCHEMBL226311 0.77 — —
SCHEMBL135961 0.77 — —
SCHEMBL9345959 0.77 DGAT1 (0.46) DGAT1ALDH1A1GAAKCNN4MEN1
SCHEMBL2616407 0.77 DGAT1 (0.46) DGAT1ALDH1A1KCNN4SRC
SCHEMBL24625927 0.76 — —
SCHEMBL361851 0.76 ALDH1A1 (0.44) DGAT1ALDH1A1GAAPDK1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9640840-B2 Sodium secondary battery PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2017-05-02 — — US claimed
US-20150155601-A1 SODIUM SECONDARY BATTERY PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2015-06-04 — — US claimed
US-12492182-B2 Hydroxytriazine compounds and pharmaceutical use thereof JAPAN TOBACCO INC. (JP) 2025-12-09 — — US disclosed
US-20240228879-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE THEREOF JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-07-11 — — US disclosed
US-20240076278-A1 HYDROXYTRIAZINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC. (JP) 2024-03-07 — — US disclosed
EP-4249519-A1 FLUORINATED PVC COPOLYMER COMPOSITIONS FOR INCREASED ULTRAVIOLET PROTECTION Mexichem Specialty Resins Inc. (US) 2023-09-27 — — EP disclosed
US-11762294-B2 Coating composition for photoresist underlayer ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2023-09-19 — — US disclosed
CN-111943848-B Preparation method and application of elexacator intermediate 苏州旺山旺水生物医药有限公司 2023-05-05 — — CN disclosed
CN-116075513-A Inhibitors of NEK7 kinase 哈利亚治疗公司 2023-05-05 — — CN disclosed
CN-115843272-A Inhibitors of NEK7 kinase 哈利亚治疗公司 2023-03-24 — — CN disclosed
EP-4046991-A1 HYDROXYTRIAZINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF Japan Tobacco Inc. (JP) 2022-08-24 — — EP disclosed
US-20110123926-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-26 — — US disclosed
US-20110118245-A1 RAF KINASE MODULATOR COMPOUNDS AND METHODS OF USE THEREOF AMBIT BIOSCIENCES CORP. 2011-05-19 — — US disclosed
WO-2011056764-A1 ISOTOPICALLY ENRICHED OR FLUORINATED IMIDAZO[2,1-B][1,3]BENZOTHIAZOLES AMBIT BIOSCIENCES CORP. (US) 2011-05-12 — — WO disclosed
US-20110076617-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-31 — — US disclosed
US-20110065040-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-17 — — US disclosed
WO-2011022473-A1 BIARYL COMPOUNDS AND METHODS OF USE THEREOF AMBIT BIOSCIENCES CORPORATION (US) 2011-02-24 — — WO disclosed
EP-2268623-A1 QUINAZOLINE DERIVATIVES AS RAF KINASE MODULATORS AND METHODS OF USE THEREOF Ambit Biosciences Corporation (US) 2011-01-05 — — EP disclosed
US-20100304296-A1 SALT AND PHOTORESIST COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-12-02 — — US disclosed
WO-2009117080-A1 QUINAZOLINE DERIVATIVES AS RAF KINASE MODULATORS AND METHODS OF USE THEREOF AMBIT BIOSCIENCES CORPORATON (US) 2009-09-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110118245-A1 RAF KINASE MODULATOR COMPOUNDS AND METHODS OF USE THEREOF BRAF, RAF1, ARAF DGAT1 2150/4885ALDH1A1 2988/4885ELANE 3842/4885
US-20100304296-A1 SALT AND PHOTORESIST COMPOSITION CONTAINING THE SAME C1S, H1-0, H1-2 DGAT1 2253/4885ALDH1A1 918/4885ELANE 807/4885
US-20110065040-A1 PHOTORESIST COMPOSITION C1R, P4HA1, C1S DGAT1 422/4885ALDH1A1 706/4885ELANE 1889/4885
US-20240076278-A1 HYDROXYTRIAZINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF PTGS1, PTGIS, PTGES DGAT1 1971/4885ALDH1A1 618/4885ELANE 3573/4885
US-12492182-B2 Hydroxytriazine compounds and pharmaceutical use thereof PTGS1, PTGIS, PTGES DGAT1 1971/4885ALDH1A1 618/4885ELANE 3573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.