Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SLC13A5 | Q86YT5 | 3/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10102 | 0.82 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1PKMSLC6A9KDM4E | |
| Citric Acid SCHEMBL7763981 | 0.82 | SLC6A9 (0.41) | ALDH1A1L3MBTL1SLC6A9KDM4EMEN1 | |
| SCHEMBL4297 | 0.78 | SLC13A5 (0.38) | SLC13A5LMNA | |
| SCHEMBL10451 | 0.75 | PPARG (0.39) | ALDH1A1SLC6A9KDM4EMEN1KMT2A | |
| SCHEMBL9499114 | 0.74 | SLC6A9 (0.39) | ALDH1A1L3MBTL1SLC6A9KDM4EMEN1 | |
| SCHEMBL3486 | 0.74 | TRPM8 (0.42) | ALDH1A1SLC6A9KDM4EMEN1KMT2A | |
| SCHEMBL10539 | 0.74 | SLC7A5 (0.52) | SLC6A9KDM4EMEN1KMT2ALMNA | |
| SCHEMBL5304100 | 0.70 | SLC13A5 (0.35) | SLC13A5KDM4ELMNA | |
| SCHEMBL3312478 | 0.69 | SLC6A2 (0.44) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| Oxalic Acid SCHEMBL10101 | 0.69 | SLC6A9 (0.47) | ALDH1A1SLC6A9NPSR1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0654264-B1 | Use of venlafaxine or of an aryloxy propanamine compound for the manufacture of a medicament for the treatment of urinary incontinence | LILLY CO ELI (US) | 2001-05-30 | — | — | EP | disclosed |
| EP-0654264-A1 | Treatment of incontinence with venlafaxine or an aryloxy propanamine compound | ELI LILLY AND COMPANY (US) | 1995-05-24 | — | — | EP | disclosed |