Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7772085 | 0.83 | KDM4E (0.34) | KDM4ELMNAALDH1A1NPC1RAB9A | |
| SCHEMBL7769584 | 0.82 | LTA4H (0.35) | KDM4ELMNATHRATHRB | |
| SCHEMBL7769001 | 0.80 | THRA (0.39) | KDM4ELMNATRPV1THRATHRB | |
| SCHEMBL8047273 | 0.79 | IL2 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL8035846 | 0.79 | LSS (0.43) | KDM4ELMNAALDH1A1KMT2ANPC1 | |
| SCHEMBL7769135 | 0.78 | PTGES (0.36) | KDM4EALDH1A1TRPV1 | |
| SCHEMBL7677366 | 0.75 | LSS (0.46) | KMT2AMEN1 | |
| SCHEMBL7772100 | 0.75 | KDM4E (0.33) | KDM4ELMNA | |
| SCHEMBL7677372 | 0.75 | LSS (0.46) | KMT2AMEN1 | |
| SCHEMBL8047705 | 0.74 | PPARD (0.38) | KDM4ELMNAALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778264-B1 | Tertiary amines having antimycotic and cholesterol lowering activity | HOFFMANN LA ROCHE (CH) | 2001-07-11 | — | — | EP | claimed |