Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035846 | 0.87 | LSS (0.43) | KDM4EACHEALDH1A1 | |
| SCHEMBL8035588 | 0.83 | EZH2 (0.35) | ACHE | |
| SCHEMBL7769001 | 0.80 | THRA (0.39) | PDE4DKDM4EPDE4B | |
| SCHEMBL7764172 | 0.79 | KDM4E (0.33) | KDM4EALDH1A1 | |
| SCHEMBL7772085 | 0.79 | KDM4E (0.34) | KDM4EBRD4ALDH1A1 | |
| SCHEMBL8044773 | 0.79 | ACHE (0.36) | PDE4DACHEMRGPRX4 | |
| SCHEMBL8903738 | 0.79 | ACHE (0.36) | PDE4DACHEMRGPRX4 | |
| SCHEMBL7772100 | 0.79 | KDM4E (0.33) | KDM4EPDE4BBRD4 | |
| SCHEMBL8047705 | 0.78 | PPARD (0.38) | KDM4EALDH1A1 | |
| SCHEMBL3676960 | 0.78 | LSS (0.52) | ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636367-B1 | Use of phenylalkylamines for producing cholesterol lowering agents | HOFFMANN LA ROCHE (CH) | 2000-03-29 | — | — | EP | claimed |