Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24774139 | 0.82 | ENPP2 (0.43) | TSHRLMNACYP3A4PTGS1 | |
| SCHEMBL7772183 | 0.78 | F2 (0.39) | F2TMPRSS4CYP1A2CYP2D6TP53 | |
| SCHEMBL5871728 | 0.73 | AOC3 (0.40) | CYP1A2CYP2D6LMNAESR1PGR | |
| SCHEMBL24810807 | 0.73 | ALDH1A1 (0.50) | F2TMPRSS4CYP1A2CYP2D6TP53 | |
| SCHEMBL11574176 | 0.71 | TSHR (0.56) | F2TMPRSS4CYP1A2CYP2D6TP53 | |
| SCHEMBL953630 | 0.70 | CHRNA7 (0.41) | CYP1A2CYP2D6LMNAESR1PGR | |
| SCHEMBL15486101 | 0.70 | HTR2A (0.40) | CYP1A2CYP2D6LMNAESR1PGR | |
| SCHEMBL11698441 | 0.70 | F2 (0.43) | F2TMPRSS4CYP1A2CYP2D6TP53 | |
| SCHEMBL7572550 | 0.69 | F2 (0.39) | F2TMPRSS4CYP1A2CYP2D6TP53 | |
| SCHEMBL626386 | 0.69 | ADRB2 (0.46) | F2TMPRSS4CYP1A2CYP2D6TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740690-B1 | MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | SYNGENTA LTD (GB) | 2001-06-20 | — | — | EP | disclosed |
| US-5739299-A | GOOD WET FASTNESS AND LIGHT FASTNESS PROPERTIES | ZENECA LIMITED (GB) | 1998-04-14 | — | — | US | disclosed |
| EP-0740690-A1 | MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | ZENECA LIMITED (GB) | 1996-11-06 | — | — | EP | disclosed |
| WO-1995020014-A1 | MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | ZENECA LIMITED (GB) | 1995-07-27 | — | — | WO | disclosed |