Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24810807 | 0.82 | ALDH1A1 (0.50) | F2TMPRSS4TP53CYP1A2CYP2D6 | |
| SCHEMBL1940689 | 0.80 | ENPP2 (0.48) | TSHRALDH1A1LMNAAKR1C3AKR1C2 | |
| SCHEMBL17044646 | 0.78 | LMNA (0.48) | CYP2D6TSHRALDH1A1CA2LMNA | |
| SCHEMBL7572550 | 0.78 | F2 (0.39) | F2TMPRSS4TP53CYP1A2CYP2D6 | |
| SCHEMBL17044641 | 0.78 | NR1I2 (0.45) | ALDH1A1CA2LMNAMAPTKDM4E | |
| SCHEMBL1597018 | 0.78 | ALDH1A1 (0.44) | ALDH1A1CA2LMNAMAPTKDM4E | |
| SCHEMBL626386 | 0.78 | ADRB2 (0.46) | F2TMPRSS4TP53CYP1A2CYP2D6 | |
| SCHEMBL7764247 | 0.78 | F2 (0.40) | F2TMPRSS4TP53CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL600649 | 0.77 | F2 (0.46) | F2TMPRSS4TP53CYP1A2CYP2D6 | |
| SCHEMBL24724078 | 0.77 | CDK1 (0.38) | ALDH1A1LMNAMAPTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740690-B1 | MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | SYNGENTA LTD (GB) | 2001-06-20 | — | — | EP | disclosed |
| EP-0740690-A1 | MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | ZENECA LIMITED (GB) | 1996-11-06 | — | — | EP | disclosed |
| WO-1995020014-A1 | MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | ZENECA LIMITED (GB) | 1995-07-27 | — | — | WO | disclosed |