Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | AGER | Q15109 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3457899 | 0.82 | ALDH1A1 (0.48) | TSHRTRPV4ALDH1A1LMNAMAPT | |
| SCHEMBL11574176 | 0.81 | TSHR (0.56) | F2TMPRSS4TP53CYP1A2CYP2D6 | |
| SCHEMBL17463073 | 0.78 | TRPV4 (0.52) | TRPV4ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL17289163 | 0.78 | ENPP2 (0.50) | LMNA | |
| SCHEMBL30003292 | 0.78 | CA2 (0.54) | TSHRALDH1A1CA2 | |
| SCHEMBL24810807 | 0.78 | ALDH1A1 (0.50) | F2TMPRSS4TP53CYP1A2CYP2D6 | |
| SCHEMBL28020890 | 0.75 | PSIP1 (0.52) | TRPV4ALDH1A1GAA | |
| SCHEMBL7772183 | 0.75 | F2 (0.39) | F2TMPRSS4TP53CYP1A2CYP2D6 | |
| SCHEMBL7572550 | 0.75 | F2 (0.39) | F2TMPRSS4TP53CYP1A2CYP2D6 | |
| SCHEMBL626386 | 0.75 | ADRB2 (0.46) | F2TMPRSS4TP53CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051168-A | TO FORM FLUOROALKYL AROMATIC COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-09-27 | — | — | US | disclosed |