Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 7/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 7/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.38 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769464 | 0.90 | CASR (0.46) | LPAR1LPAR5KMT2AMEN1MAPT | |
| SCHEMBL7610980 | 0.87 | MEN1 (0.44) | KMT2AMEN1OPRD1MAPTSMN1; SMN2 | |
| SCHEMBL7764648 | 0.86 | KMT2A (0.47) | KMT2AMEN1OPRD1MAPTSMN1; SMN2 | |
| SCHEMBL7611484 | 0.86 | ALDH1A1 (0.38) | KMT2AMEN1OPRD1MAPTSMN1; SMN2 | |
| SCHEMBL7768607 | 0.84 | SMN1; SMN2 (0.44) | KMT2AMEN1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL6027885 | 0.79 | SMN1; SMN2 (0.46) | KMT2AMEN1OPRD1SMN1; SMN2PTGES | |
| SCHEMBL7612302 | 0.76 | ALOX5 (0.45) | KMT2AMEN1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL13025048 | 0.75 | OPRK1 (0.45) | TAS2R14KMT2AMEN1OPRD1MAPT | |
| SCHEMBL7609951 | 0.74 | SMN1; SMN2 (0.36) | KMT2AMEN1OPRD1MAPTSMN1; SMN2 | |
| SCHEMBL7605451 | 0.74 | ALDH1A1 (0.44) | KMT2AMEN1MAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107944-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012462-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |