Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765121 | 0.76 | RAB9A (0.45) | KDM4EALDH1A1MAPT | |
| SCHEMBL7761478 | 0.68 | MAPT (0.42) | ALDH1A1MAPT | |
| SCHEMBL7763658 | 0.67 | MMP2 (0.47) | ALDH1A1MAPT | |
| SCHEMBL11334004 | 0.66 | ALDH1A1 (0.48) | OPRD1CHRM3SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL11595054 | 0.65 | KDM4E (0.47) | OPRM1OPRD1CHRM3KDM4EALDH1A1 | |
| Ethylbenzene SCHEMBL11334211 | 0.64 | L3MBTL1 (0.41) | OPRM1OPRD1OPRK1CHRM3SIGMAR1 | |
| Ethylbenzene SCHEMBL11595377 | 0.62 | L3MBTL1 (0.39) | OPRM1OPRD1OPRK1CHRM3SIGMAR1 | |
| SCHEMBL11341610 | 0.62 | KDM4E (0.50) | OPRM1OPRD1OPRK1SIGMAR1KDM4E | |
| SCHEMBL7195674 | 0.62 | MMP12 (0.50) | — | |
| SCHEMBL1928912 | 0.62 | TSHR (0.67) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098662-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2001-05-16 | — | — | EP | claimed |
| WO-2000004892-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2000-02-03 | — | — | WO | claimed |