Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 0.46 |
| ▸ | CA1 | P00915 | 16/20 | 0.46 |
| ▸ | CA7 | P43166 | 14/20 | 0.46 |
| ▸ | CA9 | Q16790 | 14/20 | 0.46 |
| ▸ | LSS | P48449 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7762764 | 0.84 | KDM4E (0.55) | LSSLMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7767380 | 0.82 | DRD4 (0.53) | LMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8407634 | 0.78 | HTR1A (0.52) | CA2CA1CA7CA9 | |
| SCHEMBL8621656 | 0.77 | KDM4E (0.61) | SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7762716 | 0.75 | KDM4E (0.56) | LMNASMN1; SMN2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9449928 | 0.74 | HTR1A (0.51) | KDM4E | |
| Hydrochloric Acid SCHEMBL8406359 | 0.74 | KDM4E (0.55) | LMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL6442002 | 0.74 | DRD4 (0.66) | CA2CA1CA7CA9CA12 | |
| SCHEMBL7766463 | 0.73 | HTR7 (0.61) | LMNAKDM4EALDH1A1 | |
| SCHEMBL7765547 | 0.73 | USP2 (0.56) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841330-B1 | Aminomethyl heterocyclic derivatives, process of their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-06-27 | — | — | EP | claimed |
| EP-0841330-A1 | Aminomethyl heterocyclic derivatives, process of their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-05-13 | — | — | EP | claimed |
| EP-0841330-B1 | Aminomethyl heterocyclic derivatives, process of their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-06-27 | — | — | EP | disclosed |
| US-5919784-A | ANXIETY, DEPRESSION | ADIR ET COMPAGNIE (FR) | 1999-07-06 | — | — | US | disclosed |
| EP-0841330-A1 | Aminomethyl heterocyclic derivatives, process of their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-05-13 | — | — | EP | disclosed |