Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770276 | 0.88 | LMNA (0.35) | LMNAHTTSMN1; SMN2CNR2NPY5R | |
| SCHEMBL7768591 | 0.87 | CNR2 (0.33) | LMNAHTTSMN1; SMN2MAPTCNR2 | |
| SCHEMBL7768575 | 0.87 | MEN1 (0.35) | LMNAHTTSMN1; SMN2CNR2SLC6A4 | |
| SCHEMBL7768375 | 0.82 | CNR2 (0.33) | LMNASMN1; SMN2CNR2PSMB5MTNR1A | |
| SCHEMBL7530250 | 0.74 | F2 (0.35) | SLC6A4PSMB5 | |
| SCHEMBL6027885 | 0.69 | SMN1; SMN2 (0.46) | LMNAHTTSMN1; SMN2CNR2SLC6A4 | |
| SCHEMBL7610293 | 0.67 | RAB9A (0.46) | LMNAHTTSMN1; SMN2MAPTNPY5R | |
| SCHEMBL7609951 | 0.65 | SMN1; SMN2 (0.36) | LMNAHTTSMN1; SMN2MAPTCNR2 | |
| SCHEMBL7768607 | 0.65 | SMN1; SMN2 (0.44) | LMNAHTTSMN1; SMN2MAPTNPY5R | |
| SCHEMBL7610980 | 0.65 | MEN1 (0.44) | LMNAHTTSMN1; SMN2MAPTSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107944-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012462-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |