Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769290 | 0.88 | LMNA (0.37) | LMNAHTTSMN1; SMN2CNR2NPY5R | |
| SCHEMBL7768575 | 0.84 | MEN1 (0.35) | LMNAHTTSMN1; SMN2CNR2 | |
| SCHEMBL7768591 | 0.84 | CNR2 (0.33) | LMNAHTTSMN1; SMN2CNR2 | |
| SCHEMBL7768375 | 0.81 | CNR2 (0.33) | LMNASMN1; SMN2CNR2PSMB5MTNR1A | |
| SCHEMBL7530250 | 0.71 | F2 (0.35) | PSMB5 | |
| SCHEMBL7605257 | 0.68 | KMT2A (0.41) | LMNAHTTSMN1; SMN2CNR2MTNR1A | |
| SCHEMBL7610293 | 0.66 | RAB9A (0.46) | LMNAHTTSMN1; SMN2NPY5R | |
| SCHEMBL6027885 | 0.66 | SMN1; SMN2 (0.46) | LMNAHTTSMN1; SMN2CNR2PTGES | |
| SCHEMBL7768607 | 0.65 | SMN1; SMN2 (0.44) | LMNAHTTSMN1; SMN2NPY5R | |
| SCHEMBL7768360 | 0.64 | GLA (0.41) | LMNAHTTSMN1; SMN2NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107944-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012462-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |