Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769290 | 0.82 | LMNA (0.37) | CNR2SMN1; SMN2LMNAPSMB5MTNR1A | |
| SCHEMBL7768591 | 0.82 | CNR2 (0.33) | CNR2RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7768575 | 0.82 | MEN1 (0.35) | CNR2SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL7770276 | 0.81 | LMNA (0.35) | CNR2SMN1; SMN2LMNAPSMB5MTNR1A | |
| SCHEMBL7530250 | 0.70 | F2 (0.35) | NPC1RAB9APSMB5 | |
| SCHEMBL7768605 | 0.69 | CHRNB2 (0.34) | CNR2NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7023844 | 0.69 | CASR (0.43) | CNR2NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7021515 | 0.66 | POLB (0.53) | NPC1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL7610293 | 0.65 | RAB9A (0.46) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL7769464 | 0.65 | CASR (0.46) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107944-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012462-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |