Dimethylamine

Dimethylamine

SCHEMBL7773507

CCCCCCS(=O)(=O)C1CNCCN1.CNC

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.34
PRCP P42785 2/20 0.32
CA2 P00918 1/20 0.32
GNAI3 P08754 4/20 0.31
GNAO1 P09471 4/20 0.31
GNAI1 P63096 4/20 0.31
EPHX1 P07099 1/20 0.30
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1429807 0.84 MEN1 (0.32)
SCHEMBL7348348 0.68 MAOA (0.37) FAAHCA2
SCHEMBL12649212 0.68 FAAH (0.40) FAAHCA2
Hydrochloric Acid SCHEMBL1768796 0.66 FAAH (0.39) FAAHCA2GNAI3GNAO1GNAI1
SCHEMBL5247560 0.65 LMNA (0.42) FAAHGNAI3GNAO1GNAI1EPHX1
SCHEMBL7095000 0.65 FAAH (0.34) FAAHCA2EPHX1
SCHEMBL25021954 0.65 GNAI3 (0.45) FAAHGNAI3GNAO1GNAI1EPHX1
SCHEMBL24072881 0.65 GNAI3 (0.45) FAAHGNAI3GNAO1GNAI1EPHX1
SCHEMBL24415263 0.65 APLNR (0.30)
SCHEMBL7350013 0.64 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0690051-B1 DIAZACYCLOALKANEALKYLSULFONAMIDE DERIVATIVE AZWELL INC (JP) 2001-07-18 EP disclosed
US-5716950-A NONTOXIC ANTIALLERGEN AND ANTIASTHMATIC HAVING LOW ANTIHISTAMINIC SIDE EFFECTS NIPPON SHOJI KABUSHIKI KAISHA (JP) 1998-02-10 US disclosed
EP-0690051-A1 DIAZACYCLOALKANEALKYLSULFONAMIDE DERIVATIVE NIPPON SHOJI KABUSHIKI KAISHA (JP) 1996-01-03 EP disclosed